Synthesis of Novel Phosphorus-Substituted Stable Isoindoles by a Three-Component Coupling Reaction of ortho-Phthalaldehyde, 9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-Oxide, and Primary Amines

A three-component coupling reaction of ortho-phthalaldehyde, 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide, and various primary amines readily afforded novel phosphorus-substituted stable isoindoles in good to excellent yields. The importance of the reversible ring-opening of 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide by methanolysis in the three-component coupling reaction became apparent.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Synthesis of Novel Phosphorus-Substituted Stable Isoindoles by a Three-Component Coupling Reaction of ortho-Phthalaldehyde, 9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-Oxide, and Primary Amines ; volume:07 ; number:03 ; year:2023 ; pages:394-400
SynOpen ; 07, Heft 03 (2023), 394-400

Contributor
Nakao, Michiyasu
Nakamura, Akihito
Takesue, Tomoyuki
Kitaike, Syuji
Ito, Hiro-O
Sano, Shigeki

DOI
10.1055/a-2148-9433
URN
urn:nbn:de:101:1-2023101210563809073177
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:56 AM CEST

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Associated

  • Nakao, Michiyasu
  • Nakamura, Akihito
  • Takesue, Tomoyuki
  • Kitaike, Syuji
  • Ito, Hiro-O
  • Sano, Shigeki

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