Randomized cross-over evaluation of investigator gender on pain thresholds in healthy volunteers
Abstract: Background and aims: This randomized cross-over study in healthy volunteers was designed primarily to evaluate the potential impact of investigator gender on electrical pain threshold (EPT) and corresponding pain intensity levels, and secondly to evaluate potential differences in those interventions between female and male study participants.Methods: Forty adult volunteers (22 females) were included. An electrical stimulation device was used to determine EPT levels (in pain magnitude scores) in series of three in each study participant - once by a female, and once by a male investigator - according to a predefined cross-over design schedule. Corresponding levels of pain intensity were scored on a visual analog scale (VAS) slide ruler.Results: Study data was obtained and analysed in all participants. Significantly higher EPT levels were determined by the female investigator compared with the male investigator (median 22 (IQR 12-31) vs. 8 (6-10) pain magnitude scores; p <0.0001),...
Abstract: Hintergrund und Ziele: Diese präklinische randomisierte Cross-Over-Studie wurde entwickelt, um 1) einen möglichen Einfluss des Geschlechts der Untersucher auf die Schwellenwerte für elektrische Schmerzen (EPT) und entsprechende Schmerzintensität bei gesunden Freiwilligen zu bewerten, und 2) mögliche Unterschiede bei diesen Interventionen zwischen weiblichen und männlichen Studienteilnehmern zu bewerten.Methoden: Vierzig gesunde erwachsene Freiwillige (22 Frauen) wurden eingeschlossen. Mit einem elektrischen Stimulationsgerät wurden die EPT-Spiegel in Dreierreihen bei jedem Studienteilnehmer - einmal von einem weiblichen und einmal von einem männlichen Untersucher - gemäß einem vordefinierten Cross-Over-Entwurfsplan bestimmt. Entsprechende Niveaus der Schmerzintensität wurden auf einem VAS-Lineal bewertet.Ergebnisse: Studiendaten wurden bei allen Teilnehmern erhoben und analysiert. Im Vergleich zum männlichen Untersucher wurden von der weiblichen Untersucherin signifikant höhere...
- Alternative title
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Randomisierte Cross-Over-Bewertung vom Geschlecht des Untersuchers auf die Schmerzschwelle bei gesunden Freiwilligen
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Randomized cross-over evaluation of investigator gender on pain thresholds in healthy volunteers ; volume:19 ; day:29 ; month:11 ; year:2021
GMS german medical science / Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften ; 19 (29.11.2021)
- Classification
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Medizin, Gesundheit
- Creator
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Sellgren, Engskov Anna
Lejbman, Ilja
Åkeson, Jonas
- DOI
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10.3205/000301
- URN
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urn:nbn:de:0183-0003016
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:26 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Sellgren, Engskov Anna
- Lejbman, Ilja
- Åkeson, Jonas
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