The role of CRF family peptides in the regulation of food intake and anxiety-like behavior

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Abstract: Corticotropin-releasing factor (CRF) and the urocortins (UCN1, UCN2, and UCN3) belong to the CRF family of peptides and are the major regulators of the adaptive response to internal and external stresses. The actions of CRF and UCNs are mediated through two receptor subtypes: CRF receptor 1 (CRFR1) and CRFR2. Their physiological roles, among other functions, include the regulation of food intake and anxiety-like behavior. In this review, we describe the progress that has been made towards understanding how anxiety- and depression-like behavior and food intake are regulated by CRF, UCN1, UCN2, and UCN3.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: The role of CRF family peptides in the regulation of food intake and anxiety-like behavior ; volume:2 ; number:4 ; year:2011 ; pages:275-280
Biomolecular concepts ; 2, Heft 4 (2011), 275-280

Creator: Nakayama, Naoko
Suzuki, Hajime
Li, Jiang-Bo
Atsuchi, Kaori
Tsai, Minglun
Amitani, Haruka
Asakawa, Akihiro
Inui, Akio

DOI: 10.1515/bmc.2011.022

URN: urn:nbn:de:101:1-2409241645052.136629984404

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:31 AM CEST

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Nakayama, Naoko
Suzuki, Hajime
Li, Jiang-Bo
Atsuchi, Kaori
Tsai, Minglun
Amitani, Haruka
Asakawa, Akihiro
Inui, Akio

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The role of CRF family peptides in the regulation of food intake and anxiety-like behavior

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Other Objects (12)

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NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala

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