Direct Addition of Grignard Reagents to Aliphatic Carboxylic Acids Enabled by Bulky turbo ‐Organomagnesium Anilides
Abstract: The synthesis of ketones through addition of organometallic reagents to aliphatic carboxylic acids is a straightforward strategy that is limited to organolithium reagents. More desirable Grignard reagents can be activated and controlled with a bulky aniline‐derived turbo‐Hauser base. This operationally simple procedure allows the straightforward preparation of a variety of aliphatic and perfluoroalkyl ketones alike from functionalized alkyl, aryl and heteroaryl Grignard reagents.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Direct Addition of Grignard Reagents to Aliphatic Carboxylic Acids Enabled by Bulky turbo ‐Organomagnesium Anilides ; day:27 ; month:01 ; year:2022 ; extent:1
Chemistry - a European journal ; (27.01.2022) (gesamt 1)
- Creator
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Colas, Kilian
V. D. dos Santos, A. Catarina
Kohlhepp, Stefanie V.
Mendoza, Abraham
- DOI
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10.1002/chem.202104053
- URN
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urn:nbn:de:101:1-2022012714233945472499
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:31 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Colas, Kilian
- V. D. dos Santos, A. Catarina
- Kohlhepp, Stefanie V.
- Mendoza, Abraham
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