Structure–Activity Relationship and Prediction of the Electron‐Transfer Potential of the Xanthones Series

Abstract: The structure–activity relationships of 31 xanthones were analyzed by using the ferric reducing antioxidant power (FRAP) assay to determine their electron‐transfer (ET) potential. It was proven that the ET potential of xanthones was dominated by four moieties (i.e. hydroquinone moiety, 5,6‐catechol moiety, 6,7‐catechol moiety, and 7,8‐catechol moiety) and was only slightly affected by other structural features, including a single phenolic OH group, the resorcinol moiety, the transannular dihydroxy moiety, a methoxy group, a sugar residue, an isoprenyl group, a cyclized isoprenyl group, and an isopentanol group. The results could be used to predict the ET potentials of other antioxidant xanthones.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Structure–Activity Relationship and Prediction of the Electron‐Transfer Potential of the Xanthones Series ; volume:7 ; number:9 ; year:2018 ; pages:730-736 ; extent:7
ChemistryOpen ; 7, Heft 9 (2018), 730-736 (gesamt 7)

Creator
Li, Xican
Jiang, Qian
Chen, Ban
Luo, Xiaoling
Chen, Dongfeng

DOI
10.1002/open.201800108
URN
urn:nbn:de:101:1-2022090110015377516347
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:34 AM CEST

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Associated

  • Li, Xican
  • Jiang, Qian
  • Chen, Ban
  • Luo, Xiaoling
  • Chen, Dongfeng

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