Reshaping Lipid Biochemistry by Pushing Barriers in Structural Lipidomics

Abstract: Lipidomics is a rapidly growing field with numerous examples showing the importance of lipid molecules throughout biology. It has also shed light onto the vast and complex functions performed by many lipids that possess an immense diversity in molecular structures. Mass spectrometry (MS) is the tool of choice for analyzing lipids and has been the key catalyst driving the field forward. However, MS does not yet permit true molecular lipidomics wherein the identification and quantification of lipids having defined molecular structures can be routinely achieved. Here we describe recent advances in MS‐based lipidomics that allow access to higher levels of molecular information in lipidomics experiments. These advances will form a key piece of the puzzle as the field moves towards systems characterization of lipids at the molecular level.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Reshaping Lipid Biochemistry by Pushing Barriers in Structural Lipidomics ; volume:58 ; number:20 ; year:2019 ; pages:6492-6501 ; extent:10
Angewandte Chemie / International edition. International edition ; 58, Heft 20 (2019), 6492-6501 (gesamt 10)

Creator
Porta Siegel, Tiffany
Ekroos, Kim
Ellis, Shane R.

DOI
10.1002/anie.201812698
URN
urn:nbn:de:101:1-2022071211131563175366
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:20 AM CEST

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Associated

  • Porta Siegel, Tiffany
  • Ekroos, Kim
  • Ellis, Shane R.

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