The Origins of Organellar Mapping by Protein Correlation Profiling
Abstract: Cells have a rich inner structure that is commonly explored by microscopy. Classical biochemical methods that break apart the cells and fractionate them along a gradient have now gotten a new lease on life through modern methods of mass spectrometry‐based proteomics. Their common principle is to comprehensively measure all the proteins in each of the fractions. The resulting quantitative profile then associates thousands of proteins to their cellular homes. Here, the author recounts how protein correlation profiling, the first such technique, was conceived and how it was applied to answer intricate cell biological questions.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
The Origins of Organellar Mapping by Protein Correlation Profiling ; volume:20 ; number:23 ; year:2020 ; extent:3
Proteomics ; 20, Heft 23 (2020) (gesamt 3)
- Creator
-
Mann, Matthias
- DOI
-
10.1002/pmic.201900330
- URN
-
urn:nbn:de:101:1-2022062213491199036272
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:20 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Mann, Matthias
Other Objects (12)
Paläoökologische Beiträge zur Milieuanalyse des tieferen Altpaläozoikums (Kambrium - Unterdevon) des Schwarzburger Antiklinoriums unter besonderer Berücksichtigung der Ichnofauna
Plasma proteome profiling to assess human health and disease
Profiling cellular E3 ubiquitin ligase networks
Biological and translational cancer proteomics
Mouse models for aberrant NF-kB activation in B-cell development and lymphomagenesis
Genetic analysis of Drosophila adult muscle type specification
Gleichheitsanalyse von Ausdrücken in nicht-strikten funktionalen Programmiersprachen unter Verwendung der Kontextanalyse
Ovarian cancer proteomics
Data acquisition methods for next-generation mass spectrometry-based proteomics
Analysis of aging by quantitative proteomics and mitochondrial organellar proteomics
Pathology enters the proteomic era : cell-type resolved mass spectrometry to unravel mechanisms of disease
Development and application of software and algorithms for network approaches to proteomics data analysis
Paläoökologische Beiträge zur Milieuanalyse des tieferen Altpaläozoikums (Kambrium - Unterdevon) des Schwarzburger Antiklinoriums unter besonderer Berücksichtigung der Ichnofauna
Plasma proteome profiling to assess human health and disease
Profiling cellular E3 ubiquitin ligase networks
Biological and translational cancer proteomics
Mouse models for aberrant NF-kB activation in B-cell development and lymphomagenesis
Genetic analysis of Drosophila adult muscle type specification
Gleichheitsanalyse von Ausdrücken in nicht-strikten funktionalen Programmiersprachen unter Verwendung der Kontextanalyse
Ovarian cancer proteomics
Data acquisition methods for next-generation mass spectrometry-based proteomics
Analysis of aging by quantitative proteomics and mitochondrial organellar proteomics
Pathology enters the proteomic era : cell-type resolved mass spectrometry to unravel mechanisms of disease
Development and application of software and algorithms for network approaches to proteomics data analysis
Paläoökologische Beiträge zur Milieuanalyse des tieferen Altpaläozoikums (Kambrium - Unterdevon) des Schwarzburger Antiklinoriums unter besonderer Berücksichtigung der Ichnofauna
Plasma proteome profiling to assess human health and disease
Profiling cellular E3 ubiquitin ligase networks
Biological and translational cancer proteomics
Mouse models for aberrant NF-kB activation in B-cell development and lymphomagenesis
Genetic analysis of Drosophila adult muscle type specification
Gleichheitsanalyse von Ausdrücken in nicht-strikten funktionalen Programmiersprachen unter Verwendung der Kontextanalyse
Ovarian cancer proteomics
Data acquisition methods for next-generation mass spectrometry-based proteomics
Analysis of aging by quantitative proteomics and mitochondrial organellar proteomics
Pathology enters the proteomic era : cell-type resolved mass spectrometry to unravel mechanisms of disease