Semi‐Telechelic Polymers from Mechanochemical C─C Bond Activation

Abstract: Unstrained C─C bond activation is attained in homopolymers through mechanochemical bond scission followed by functionalization to yield mostly semi‐telechelic polymer chains. Ball milling poly (ethylene oxide) (PEO) in the presence of 1‐(bromoacetyl) pyrene (BAPy) yields the pyrene terminated PEO. Similarly, milling with 2,4′‐dibromoacetophenone followed by Suzuki coupling allows the introduction of various aryl end groups. PEOs with a molecular weight below 20 kDa show no functionalization, supporting a mechanochemical mechanism. The protocol is also tested with doxorubicin, yielding the drug‐polymer conjugate. PEO halogenation is also demonstrated by milling PEO with iodine, N‐bromosuccinimide, or N‐iodosuccinimide, which can then be reacted with an amine substituted anthracene. Grinding additional carbon polymers with BAPy indicates that this functionalization method is general for different polymer chemistries.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Semi‐Telechelic Polymers from Mechanochemical C─C Bond Activation ; day:23 ; month:10 ; year:2023 ; extent:7 ; Advanced science ; (23.10.2023) (gesamt 7)

Contributors, Places and Time

• Creator: Schwarz, Rony ; Diesendruck, Charles E.

Further information

• DOI: 10.1002/advs.202304571
• URN: urn:nbn:de:101:1-2023102315354865844357
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 11:01 AM CEST