Genetic analysis of platelet-derived growth factor receptor-like gene (<italic>PDGFRL</italic>) polymorphism and melanin traits in Lanping black-boned sheep (<italic>Ovis aries</italic>)

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Abstract P < 0.05). We also identified three synonymous mutation sites within a partial 1128 bp exon fragment of the gene-encoding PDGFRL/P < 0.05). The discernment of GG, TT, and GG as the prevailing genotypes at their respective genetic loci in Lanping black-boned sheep heralds a breakthrough in our understanding of the genetic markers associated with black pigmentation. However, all three loci are silent mutations and do not alter the phenotypic changes. Whether they affect changes in melanin content through other metabolic pathways requires further study. In conclusion, the PDGFRL gene was silenced by mutations in our study and affected blood melanin levels. However, the gene did not undergo a missense mutation that altered the phenotypic changes, and the exact channel through which the changes in melanin content were affected needs to be further verified.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Genetic analysis of platelet-derived growth factor receptor-like gene (PDGFRL) polymorphism and melanin traits in Lanping black-boned sheep (Ovis aries) ; volume:67 ; number:3 ; year:2024 ; pages:383-392 ; extent:10
Archives animal breeding ; 67, Heft 3 (2024), 383-392 (gesamt 10)

Creator
Yue, Dan
Peng, Chaochao
Memon, Sameeullah
Iqbal, Azeem
Xiong, Heli
He, Xiaoming
Lu, Ying
Deng, Weidong

DOI
10.5194/aab-67-383-2024
URN
urn:nbn:de:101:1-2408080415292.285165707672
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:53 AM CEST

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Associated

  • Yue, Dan
  • Peng, Chaochao
  • Memon, Sameeullah
  • Iqbal, Azeem
  • Xiong, Heli
  • He, Xiaoming
  • Lu, Ying
  • Deng, Weidong

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