Enzyme‐Enabled Droplet Biobattery for Powering Synthetic Tissues

Abstract: Enzyme‐enabled biobatteries are promising green options to power the next‐generation of bioelectronics and implantable medical devices. However, existing power sources based on enzymatic biofuel chemistry exhibit limited scale‐down feasibility due to the solid and bulky battery structures. Therefore, miniature and soft alternatives are needed for integration with implants and tissues. Here, a biobattery built from nanolitre droplets, fuelled by the enzyme‐enabled oxidation of reduced nicotinamide adenine dinucleotide, generates electrical outputs and powers ion fluxes in droplet networks. Optimization of the droplet biobattery components ensures a stable output current of ~13,000 pA for over 24 h, representing a more than 600‐fold increase in output over previous approaches, including light‐driven processes. The enzyme‐enabled droplet biobattery opens new avenues in bioelectronics and bioiontronics, exemplified by tasks such as the ability to drive chemical signal transmission in integrated synthetic tissues.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Enzyme‐Enabled Droplet Biobattery for Powering Synthetic Tissues ; day:03 ; month:09 ; year:2024 ; extent:7
Angewandte Chemie ; (03.09.2024) (gesamt 7)

Urheber
Liu, Juan
Qing, Yujia
Zhou, Linna
Chen, Shaomeng
Li, Xuefei
Zhang, Yujia
Bayley, Hagan

DOI
10.1002/ange.202408665
URN
urn:nbn:de:101:1-2409041404320.630983161421
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 10:09 MESZ

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Beteiligte

  • Liu, Juan
  • Qing, Yujia
  • Zhou, Linna
  • Chen, Shaomeng
  • Li, Xuefei
  • Zhang, Yujia
  • Bayley, Hagan

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