Novel immunotherapies in multiple myeloma – chances and challenges

Abstract: In this review article, we summarize the latest data on antibody-drug conjugates, bispecific T-cell-engaging antibodies, and chimeric antigen receptor T cells in the treatment of multiple myeloma. We discuss the pivotal questions to be addressed as these new immunotherapies become standard agents in the management of multiple myeloma. We also focus on the selection of patients for these therapies and speculate as to how best to individualize treatment approaches. We see these novel immunotherapies as representing a paradigm shift. However, despite the promising preliminary data, many open issues remain to be evaluated in future trials

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Haematologica. - 106, 10 (2021) , 2555-2565, ISSN: 1592-8721

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2021

DOI
10.3324/haematol.2020.266858
URN
urn:nbn:de:bsz:25-freidok-2195050
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:52 PM CET

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Time of origin

  • 2021

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