Preliminary validation system for cuffless blood pressure measurement

Abstract: The development of a non-invasive, cuffless, continuous, wearable device for the measurement of blood pressure is a complex endeavour due to the high specificity at each measuring site and the need for high accuracy. Proof-ofconcept and validation of a prototype should be performed at an early stage for functionality assessment. Additionally, the emergence of biological computer models allows for in-silico research, which results should be verified in a practical experiment. To grant an optimal preliminary assessment of a prototype, this work aimed to develop and validate accurate in-vitro and ex-vivo arterial models, with simple construction and easily available components. The comparison between a silicone tube and a porcine artery as a mimicked human radial artery was based on the stiffness parameter. Flow pressure is controlled by a centrifugal heart-like pump. Pressure values are extracted with ultrasound and a commercial piezoresistive pressure sensor is used for pressure validation. The porcine artery showed much more realistic stiffness values (·=15.360) than the silicon tube (·=543.420), which was very stiff in comparison to the typical in-vivo radial artery stiffness (·=9.5). The decrease in stiffness of 97.173 % (from the silicone tube to the porcine artery) led to an acute decrease in the derived pressure error. This work serves as guidelines for the development of a low-budget arm phantom, as the simple setup allowed for a primary validation of a proof-of-concept ultrasound-based sensor for the measurement of pressure.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Preliminary validation system for cuffless blood pressure measurement ; volume:8 ; number:2 ; year:2022 ; pages:189-192 ; extent:4 ; Current directions in biomedical engineering ; 8, Heft 2 (2022), 189-192 (gesamt 4)

Contributors, Places and Time

• Creator: Gonçalves Seabra, Ana Carolina ; Ferreira da Silva, Alexandre ; Stieglitz, Thomas ; Belen Amado-Rey, Ana

Further information

• DOI: 10.1515/cdbme-2022-1049
• URN: urn:nbn:de:101:1-2022090315404186553991
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:27 AM CEST