Consensus statement on extracellular vesicles in liquid biopsy for advancing laboratory medicine

Abstract: Extracellular vesicles (EVs) represent a diverse class of nanoscale membrane vesicles actively released by cells. These EVs can be further subdivided into categories like exosomes and microvesicles, based on their origins, sizes, and physical attributes. Significantly, disease-derived EVs have been detected in virtually all types of body fluids, providing a comprehensive molecular profile of their cellular origins. As a result, EVs are emerging as a valuable addition to liquid biopsy techniques. In this collective statement, the authors share their current perspectives on EV-related research and product development, with a shared commitment to translating this newfound knowledge into clinical applications for cancer and other diseases, particularly as disease biomarkers. The consensus within this document revolves around the overarching recognition of the merits, unresolved questions, and existing challenges surrounding EVs. This consensus manuscript is a collaborative effort led by the Committee of Exosomes, Society of Tumor Markers, Chinese anti-Cancer Association, aimed at expediting the cultivation of robust scientific and clinically applicable breakthroughs and propelling the field forward with greater swiftness and efficacy.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Consensus statement on extracellular vesicles in liquid biopsy for advancing laboratory medicine ; volume:63 ; number:3 ; year:2025 ; pages:465-482 ; extent:018
Clinical chemistry and laboratory medicine ; 63, Heft 3 (2025), 465-482 (gesamt 018)

Urheber
Dong, Xingli
Lin, Yusheng
Li, Kai
Liang, Gaofeng
Huang, Xiaoyi
Pan, Jingxuan
Wang, Lu
Zhang, Dongmei
Liu, Tingjiao
Wang, Tong
Yan, Xiaomei
Zhang, Long
Li, Xiaowu
Qu, Xiujuan
Jia, Da
Li, Yong
Zhang, Hao

DOI
10.1515/cclm-2024-0188
URN
urn:nbn:de:101:1-2501290501192.671012224991
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:35 MESZ

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Beteiligte

  • Dong, Xingli
  • Lin, Yusheng
  • Li, Kai
  • Liang, Gaofeng
  • Huang, Xiaoyi
  • Pan, Jingxuan
  • Wang, Lu
  • Zhang, Dongmei
  • Liu, Tingjiao
  • Wang, Tong
  • Yan, Xiaomei
  • Zhang, Long
  • Li, Xiaowu
  • Qu, Xiujuan
  • Jia, Da
  • Li, Yong
  • Zhang, Hao

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