Microwave-induced rapid formation of biomimetic hydroxyapatite coating on gelatin-siloxane hybrid microspheres in 10X-SBF solution
Abstract: Bioactive materials can attract calcium and phosphate ions in simulated body fluid (SBF) solution to mimic the composition of extracellular matrix (ECM). Rapid biodegradation rate of natural polymers in contact with water-based solutions and time-consuming process of mineralization in SBF led to using concentrated simulated media. Herein, gelatin-siloxane microspheres were fabricated via single emulsion method. Then hybrid spheres were immersed in the modified 10X-SBF solution, and microwave energy (600 W) was expanded for the rapid formation of hydroxyapatite (HA) on the spheres. Results indicated homogeneous coating of microspheres and high similarity of synthesized HA to the bone composition. Increasing intensity of HA-related peaks in Fourier transform infrared spectrum, X-ray diffraction and surface roughness after utilizing microwave-assisted method confirmed high efficiency of this technique in biomimetic mineralization of structures. Cell culture studies with human osteosarcoma cell lines (MG-63) demonstrated that mineralized HA in 10X-SBF solution under microwave treatment could be able to mimic bone ECM for tissue regeneration applications in the shortest time and highest similarity to the natural tissue.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Microwave-induced rapid formation of biomimetic hydroxyapatite coating on gelatin-siloxane hybrid microspheres in 10X-SBF solution ; volume:18 ; number:3 ; year:2018 ; pages:247-255 ; extent:9
e-Polymers ; 18, Heft 3 (2018), 247-255 (gesamt 9)
- Urheber
-
Ghorbani, Farnaz
Zamanian, Ali
Behnamghader, Aliasghar
Joupari, Morteza Daliri
- DOI
-
10.1515/epoly-2017-0196
- URN
-
urn:nbn:de:101:1-2412151601380.242496335392
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:30 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Ghorbani, Farnaz
- Zamanian, Ali
- Behnamghader, Aliasghar
- Joupari, Morteza Daliri
Ähnliche Objekte (12)
QbD‐Based Fabrication of Biomimetic Hydroxyapatite Embedded Gelatin Nanoparticles for Localized Drug Delivery against Deteriorated Arthritic Joint Architecture
Synthetic Hydroxyapatite as a Biomimetic Oral Care Agent
Microfluidic device with a carbonate‐rich hydroxyapatite micro‐coating
Gefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coatingGefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coating
Synovial fluid-inspired biomimetic lubricating microspheres: Zwitterionic polyelectrolyte brushes-grafted microgels
Gelatin-based composite hydrogels with biomimetic lubrication and sustained drug release
High performance nano hydroxyapatite coating on zinc for biomedical applications
Behavior of osteoblasts on the surfaces of nanocrystalline hydroxyapatite coating
Process optimization for the rapid conversion of calcite into hydroxyapatite microspheres for chromatographic applications
Biomimetic ion substituted and Co-substituted hydroxyapatite nanoparticle synthesis using Serratia Marcescens
Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method
A self-organising biomimetic collagen/nano-hydroxyapatite-glycosaminoglycan scaffold for spinal fusion
QbD‐Based Fabrication of Biomimetic Hydroxyapatite Embedded Gelatin Nanoparticles for Localized Drug Delivery against Deteriorated Arthritic Joint Architecture
Synthetic Hydroxyapatite as a Biomimetic Oral Care Agent
Microfluidic device with a carbonate‐rich hydroxyapatite micro‐coating
Gefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coatingGefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coating
Synovial fluid-inspired biomimetic lubricating microspheres: Zwitterionic polyelectrolyte brushes-grafted microgels
Gelatin-based composite hydrogels with biomimetic lubrication and sustained drug release
High performance nano hydroxyapatite coating on zinc for biomedical applications
Behavior of osteoblasts on the surfaces of nanocrystalline hydroxyapatite coating
Process optimization for the rapid conversion of calcite into hydroxyapatite microspheres for chromatographic applications
Biomimetic ion substituted and Co-substituted hydroxyapatite nanoparticle synthesis using Serratia Marcescens
Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method
A self-organising biomimetic collagen/nano-hydroxyapatite-glycosaminoglycan scaffold for spinal fusion
QbD‐Based Fabrication of Biomimetic Hydroxyapatite Embedded Gelatin Nanoparticles for Localized Drug Delivery against Deteriorated Arthritic Joint Architecture
Synthetic Hydroxyapatite as a Biomimetic Oral Care Agent
Microfluidic device with a carbonate‐rich hydroxyapatite micro‐coating
Gefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coatingGefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coating
Synovial fluid-inspired biomimetic lubricating microspheres: Zwitterionic polyelectrolyte brushes-grafted microgels
Gelatin-based composite hydrogels with biomimetic lubrication and sustained drug release
High performance nano hydroxyapatite coating on zinc for biomedical applications
Behavior of osteoblasts on the surfaces of nanocrystalline hydroxyapatite coating
Process optimization for the rapid conversion of calcite into hydroxyapatite microspheres for chromatographic applications
Biomimetic ion substituted and Co-substituted hydroxyapatite nanoparticle synthesis using Serratia Marcescens
Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method