A Chiral Sulfoxide-Based C–H Acid

We report the design and synthesis of a strong, chiral, enantiopure sulfoxide-based C–H acid. Single-crystal X-ray analysis confirms the proposed structure and its absolute configuration. The new motif shows a high acidity and activity in Brønsted and Lewis acid catalyzed transformations. So far, only little to no enantioselectivities were achieved.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
A Chiral Sulfoxide-Based C–H Acid ; volume:33 ; number:01 ; year:2022 ; pages:45-47
Synlett ; 33, Heft 01 (2022), 45-47

Contributor
Höfler, Denis
Kaupmees, Karl
Leito, Ivo
List, Benjamin

DOI
10.1055/a-1695-4516
URN
urn:nbn:de:101:1-2022031915274820269066
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:21 AM CEST

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Associated

  • Höfler, Denis
  • Kaupmees, Karl
  • Leito, Ivo
  • List, Benjamin

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