Advances in Imaging Modalities for Pediatric Brain and Spinal Cord Tumors

Background: Neuroimaging has evolved from anatomical imaging toward a multi-modality comprehensive anatomical and functional imaging in the past decades, important functional data like perfusion-weighted imaging, permeability imaging, diffusion-weighted imaging (DWI), and diffusion tensor imaging (DTI), tractography, metabolic imaging, connectomics, event-related functional imaging, resting state functional imaging, and much more is now being offered. Summary: Precision diagnostics has proven to be essential for precision treatment. Many minimal invasive techniques have been developed, taking advantage of digital subtraction angiography and interventional neuroradiology. Furthermore, intraoperative CT and/or MRI and more recently MR-guided focused ultrasound have complemented the diagnostic and therapeutic armamentarium. Key Messages: In the current manuscript, we discuss standard imaging sequences including advanced techniques like DWI, DTI, susceptibility-weighted imaging, and 1H magnetic resonance spectroscopy, various perfusion weighted imaging approaches including arterial spin labeling, dynamic contrast enhanced imaging, and dynamic susceptibility contrast imaging. Pre-, intra, and postoperative surgical imaging including visualize imaging will be discussed. The value of connectomics will be presented for its value in neuro-oncology. Minimal invasive therapeutic possibilities of interventional neuroradiology and image-guided laser ablation and MR-guided high-intensity-focused ultrasound will be presented for treatment of pediatric brain and spinal cord tumors. Finally, a comprehensive review of spinal cord tumors and matching neuropathology has been included.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Advances in Imaging Modalities for Pediatric Brain and Spinal Cord Tumors ; volume:58 ; number:5 ; year:2023 ; pages:240-258 ; extent:19 ; Pediatric neurosurgery ; 58, Heft 5 (2023), 240-258 (gesamt 19)

Contributors, Places and Time

• Creator: Huisman, Thierry A.G.M. ; Patel, Rajan ; Kralik, Stephen ; Desai, Nilesh K. ; Meoded, Avner ; Chen, Karen ; Weiner, Howard L. ; Curry, Daniel J. ; Lequin, Maarten ; Kranendonk, Mariette ; Orman, Gunes ; Jallo, George

Further information

• DOI: 10.1159/000531998
• URN: urn:nbn:de:101:1-2023120623153951081625
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:32 AM CEST