Early MRI imaging and follow-up study in cerebral amyloid angiopathy
Aim: To study the imaging features of leukoaraiosis (LA) and hemorrhage in cerebral amyloid angiopathy (CAA) patients. Methods: The earliest MRI images of probable CAA patients and non-CAA patients were collected. The characteristics of LA in the two groups were analyzed. Cerebral micro bleeding (CMB), superficial siderosis (SS), and intracranial hemorrhage (ICH) were recorded in the follow-up study. The space relationship between CMB or SS and ICH was assessed. Results: We found that 10/21 (47.6%) patients had occipital prominent LA and 14/21 (66.7%) patients had subcortical punctate LA before the ICH, which was higher than that of the ones in the control group (p = 0.015 and 0.038, respectively). The recurrence rate of ICH was 100% (3/3) in patients with diffuse SS and 36.4% (4/11) in patients without. The recurrence rate of ICH was 60% (3/5) in patients with multiple-lobe CMBs and 44.4% (4/9) in those without. The location of the ICH and CMB was inconsistent. ICH occurred in the ipsilateral cerebral hemisphere of SS in three patients with diffuse SS. Conclusion: LA, diffuse SS, and multiple-lobe CMBs are important imaging characteristics of CAA, which may help make early diagnosis and predict the recurrence of ICH.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Early MRI imaging and follow-up study in cerebral amyloid angiopathy ; volume:16 ; number:1 ; year:2021 ; pages:257-263 ; extent:7
Open medicine ; 16, Heft 1 (2021), 257-263 (gesamt 7)
- Creator
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Zhang, Shan-chun
Jia, Jian-jun
Zhao, Heng-li
Zhou, Bo
Wang, Wei
Lu, Xiang-hui
Wang, Hao
Wang, Zhen-fu
Wu, Wei-ping
- DOI
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10.1515/med-2021-0212
- URN
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urn:nbn:de:101:1-2022092015525675997104
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:22 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Zhang, Shan-chun
- Jia, Jian-jun
- Zhao, Heng-li
- Zhou, Bo
- Wang, Wei
- Lu, Xiang-hui
- Wang, Hao
- Wang, Zhen-fu
- Wu, Wei-ping
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