Cutaneous mucormycosis of the lower extremity leading amputation in two diabetic patients
Mucormycosis is an invasive, rapidly progressive, life-threatening fungal infection, with a propensity for diabetic, immunosuppressed, and trauma patients. The classic rhinocerebral variation is most common in diabetic patients. While the cutaneous form is usually caused by direct inoculation in immunocompetent patients. Cutaneous mucormycosis manifests in soft tissue and risks involvement of underlying structures. Tibial osteomyelitis can also occur secondary to cutaneous mucormycosis but is rare. Limb salvage is typically successful after lower extremity cutaneous mucormycosis even when the bone is involved. Herein, we report two cases of lower extremity cutaneous mucormycosis in diabetic patients that presented as acute worsening of chronic pretibial ulcers. Despite aggressive antifungal therapy and surgical debridement, both ultimately required amputation. Such aggressive presentation has not been reported in the absence of major penetrating trauma, recent surgery, or burns.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Cutaneous mucormycosis of the lower extremity leading amputation in two diabetic patients ; volume:48 ; number:02 ; year:2021 ; pages:231-236
Archives of Plastic Surgery ; 48, Heft 02 (2021), 231-236
- Contributor
-
Coerdt, Kathleen M.
Zolper, Elizabeth G.
Starr, Amy G.
Fan, Kenneth L.
Attinger, Christopher E.
Evans, Karen K.
- DOI
-
10.5999/aps.2020.00549
- URN
-
urn:nbn:de:101:1-2022042908570881350655
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:34 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Coerdt, Kathleen M.
- Zolper, Elizabeth G.
- Starr, Amy G.
- Fan, Kenneth L.
- Attinger, Christopher E.
- Evans, Karen K.
Other Objects (12)
Primary cutaneous mucormycosis of the scalp
Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
Gastrointestinal Mucormycosis
Colonic mucormycosis
Cutaneous Mucormycosis Resulting from Hematogenous Dissemination of Rhizomucor pusillus in an Immunocompromised Patient
Amputation in Trauma—How to Achieve a Good Result from Lower Extremity Amputation Irrespective of the Level
Long-term outcome following upper extremity replantation after major traumatic amputation
Use of Physical Activity Measures in Rehabilitation Interventions Following Lower Extremity Amputation
Up and down waves of glycemic control and lower-extremity amputation in diabetes
Mucormycosis: An Uncommon Cutaneous Infection at Permanent Pacemaker-Implanted Site in a Very Low-Birthweight Baby
Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark
The Mangled Extremity Severity Score (MESS) does not predict amputation in popliteal artery injury
Primary cutaneous mucormycosis of the scalp
Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
Gastrointestinal Mucormycosis
Colonic mucormycosis
Cutaneous Mucormycosis Resulting from Hematogenous Dissemination of Rhizomucor pusillus in an Immunocompromised Patient
Amputation in Trauma—How to Achieve a Good Result from Lower Extremity Amputation Irrespective of the Level
Long-term outcome following upper extremity replantation after major traumatic amputation
Use of Physical Activity Measures in Rehabilitation Interventions Following Lower Extremity Amputation
Up and down waves of glycemic control and lower-extremity amputation in diabetes
Mucormycosis: An Uncommon Cutaneous Infection at Permanent Pacemaker-Implanted Site in a Very Low-Birthweight Baby
Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark
The Mangled Extremity Severity Score (MESS) does not predict amputation in popliteal artery injury
Primary cutaneous mucormycosis of the scalp
Non-COVID-19 Cutaneous Mucormycosis from a Plastic Surgical Perspective
Gastrointestinal Mucormycosis
Colonic mucormycosis
Cutaneous Mucormycosis Resulting from Hematogenous Dissemination of Rhizomucor pusillus in an Immunocompromised Patient
Amputation in Trauma—How to Achieve a Good Result from Lower Extremity Amputation Irrespective of the Level
Long-term outcome following upper extremity replantation after major traumatic amputation
Use of Physical Activity Measures in Rehabilitation Interventions Following Lower Extremity Amputation
Up and down waves of glycemic control and lower-extremity amputation in diabetes
Mucormycosis: An Uncommon Cutaneous Infection at Permanent Pacemaker-Implanted Site in a Very Low-Birthweight Baby
Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark