Ruthenium Catalyzed N ‐Alkylation of Cyclic Amines with Primary Alcohols
A robust alcohol amination protocol using common saturated amines and primary alcohols as starting materials is described. The reactions are catalyzed by combination of dichloro (p‐cymene) ruthenium (II) dimer precatalyst with triphenylphosphine ligand, with the excess alcohol substrate or toluene functioning as the solvent. The catalyst and ligand residues can be precipitated from the reaction media by addition of hexane or cold diethyl ether, followed by precipitation and isolation of the product as a hydrochloride salt.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Ruthenium Catalyzed N ‐Alkylation of Cyclic Amines with Primary Alcohols ; volume:2020 ; number:20 ; year:2020 ; pages:3030-3040 ; extent:11
European journal of organic chemistry ; 2020, Heft 20 (2020), 3030-3040 (gesamt 11)
- Creator
- DOI
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10.1002/ejoc.202000167
- URN
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urn:nbn:de:101:1-2022062706493853729866
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:35 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Savela, Risto
- Vogt, Dieter
- Leino, Reko
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