The Choice of Nanoparticle Surface‐Coupled Fluorescent Dyes Impacts Cellular Interaction

Abstract: Fluorescently‐labelled nanoparticles show great promise for nanoparticle tracking and detection in biological or medical applications. However, these fluorescent molecules functionalized on the surface of the nanoparticles can impact the interaction of nanoparticles with biomolecules, cells, and subsequently influence their uptake. To explore the extent of these interactions, PEGylated gold nanoparticles were functionalized with six structurally different fluorescent dyes to demonstrate that the presence of the dye alters nanoparticle behavior, in particular interactions with bovine serum albumin, which consequently influenced their cellular uptake.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
The Choice of Nanoparticle Surface‐Coupled Fluorescent Dyes Impacts Cellular Interaction ; day:13 ; month:12 ; year:2021 ; extent:1
ChemNanoMat ; (13.12.2021) (gesamt 1)

Creator
Milošević, Ana
Haeni, Laetitia
Ackermann Hirschi, Liliane
Vanni, Stefano
Campomanes‐Ramos, Pablo
Rothen-Rutishauser, Barbara
Rodriguez‐Lorenzo, Laura
Petri‐Fink, Alke

DOI
10.1002/cnma.202100443
URN
urn:nbn:de:101:1-2021121414020587411403
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:24 AM CEST

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