Functional Characterisation of Highly Conserved and Structurally Prominent Residues of 2‐Methylisoborneol Synthase
Abstract: 2‐Methylisoborneol is a widespread musty odourant that is produced by many bacteria including actinomycetes, cyanobacteria and myxobacteria. Two 2‐methylisoborneol synthases (MIBS) that are phylogenetically distant to the known enzyme from Streptomyces coelicolor were found to be highly active for 2‐methylisoborneol biosynthesis. Based on the enzyme structure and on an amino acid sequence alignment, the MIBS from S. coelicolor was extensively studied through site‐directed mutagenesis.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Functional Characterisation of Highly Conserved and Structurally Prominent Residues of 2‐Methylisoborneol Synthase ; day:20 ; month:04 ; year:2023 ; extent:10
Chemistry - a European journal ; (20.04.2023) (gesamt 10)
- Urheber
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Gu, Binbin
Dickschat, Jeroen S.
- DOI
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10.1002/chem.202300775
- URN
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urn:nbn:de:101:1-2023051715104641234214
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 11:02 MESZ
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Beteiligte
- Gu, Binbin
- Dickschat, Jeroen S.
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