Colonic Dilatation Complicating Acute Severe Ulcerative Colitis Managed Successfully with Accelerated Infliximab Dosing
Lately, emerging data suggest an association between the development of inflammatory bowel disease and anti-interleukin-17 therapy. Megacolon is a life-threatening complication of acute severe ulcerative colitis (ASUC), but its treatment has not yet been established in current practice guidelines. We report a rare case of known psoriasis treated by secukinumab in a patient who presented with ASUC and colonic dilatation. Neither steroids nor standard infliximab regimen was effective. Finally, rescue therapy with accelerated infliximab strategy resulted in excellent recovery. In certain cases of steroid-refractory ASUC complicated by megacolon, accelerated infliximab regimen can be an alternative to surgery.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Colonic Dilatation Complicating Acute Severe Ulcerative Colitis Managed Successfully with Accelerated Infliximab Dosing ; volume:17 ; number:1 ; year:2023 ; pages:82-88 ; extent:7
Case reports in gastroenterology ; 17, Heft 1 (2023), 82-88 (gesamt 7)
- Creator
-
Bui, Hoang Huu
Dang, Luan Minh
Vo, Diem Thi-Ngoc
Nguyen, Chuong Dinh
- DOI
-
10.1159/000529152
- URN
-
urn:nbn:de:101:1-2024010323384650990545
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:25 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Bui, Hoang Huu
- Dang, Luan Minh
- Vo, Diem Thi-Ngoc
- Nguyen, Chuong Dinh
Other Objects (12)
Mediastinal abscess complicating esophageal dilatation: a case report
Infliximab in young paediatric IBD patients: it is all about the dosing
Two cases of perforated corneal ulcers complicating rheumatoid arthritis treated successfully by biological therapy
Pancreatic pseudocyst with complicating colonic fistula successfully closed using the over-the-scope-clip system
Cutaneous protothecosis in a dog successfully treated with oral itraconazole in pulse dosing
A Novel Case of Multicentric Reticulohistiocytosis Associated with Renal Cell Carcinoma Successfully Treated with Infliximab and Methotrexate
Correction to: Cutaneous protothecosis in a dog successfully treated with oral itraconazole in pulse dosing
Pulmonary Hypertension Complicating Pregnancy
Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases
Dilatation benigner Ösophagusstenosen
Constrictive pericarditis complicating cardiac transplantation
Pulmonary hypertension complicating pulmonary sarcoidosis
Mediastinal abscess complicating esophageal dilatation: a case report
Infliximab in young paediatric IBD patients: it is all about the dosing
Two cases of perforated corneal ulcers complicating rheumatoid arthritis treated successfully by biological therapy
Pancreatic pseudocyst with complicating colonic fistula successfully closed using the over-the-scope-clip system
Cutaneous protothecosis in a dog successfully treated with oral itraconazole in pulse dosing
A Novel Case of Multicentric Reticulohistiocytosis Associated with Renal Cell Carcinoma Successfully Treated with Infliximab and Methotrexate
Correction to: Cutaneous protothecosis in a dog successfully treated with oral itraconazole in pulse dosing
Pulmonary Hypertension Complicating Pregnancy
Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases
Dilatation benigner Ösophagusstenosen
Constrictive pericarditis complicating cardiac transplantation
Pulmonary hypertension complicating pulmonary sarcoidosis
Mediastinal abscess complicating esophageal dilatation: a case report
Infliximab in young paediatric IBD patients: it is all about the dosing
Two cases of perforated corneal ulcers complicating rheumatoid arthritis treated successfully by biological therapy
Pancreatic pseudocyst with complicating colonic fistula successfully closed using the over-the-scope-clip system
Cutaneous protothecosis in a dog successfully treated with oral itraconazole in pulse dosing
A Novel Case of Multicentric Reticulohistiocytosis Associated with Renal Cell Carcinoma Successfully Treated with Infliximab and Methotrexate
Correction to: Cutaneous protothecosis in a dog successfully treated with oral itraconazole in pulse dosing
Pulmonary Hypertension Complicating Pregnancy
Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases
Dilatation benigner Ösophagusstenosen
Constrictive pericarditis complicating cardiac transplantation