Cell sorters see things more clearly now

Microscopy and fluorescence‐activated cell sorting (FACS) are two of the most important tools for single‐cell phenotyping in basic and biomedical research. Microscopy provides high‐resolution snapshots of cell morphology and the inner workings of cells, while FACS isolates thousands of cells per second using simple parameters, such as the intensity of fluorescent protein labels. Recent technologies are now combining both methods to enable the fast isolation of cells with microscopic phenotypes of interest, thereby bridging a long‐standing gap in the life sciences. In this Commentary, we discuss the technical advancements made by image‐enabled cell sorting and highlight novel experimental strategies in functional genomics and single‐cell research.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Cell sorters see things more clearly now ; day:13 ; month:02 ; year:2023 ; extent:4
Molecular systems biology ; (13.02.2023) (gesamt 4)

Creator
Schraivogel, Daniel
Steinmetz, Lars M.

DOI
10.15252/msb.202211254
URN
urn:nbn:de:101:1-2023021314281854030282
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:49 AM CEST

Data provider

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Associated

  • Schraivogel, Daniel
  • Steinmetz, Lars M.

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