Synthetic Cells: From Simple Bio‐Inspired Modules to Sophisticated Integrated Systems
Abstract: Bottom‐up synthetic biology is the science of building systems that mimic the structure and function of living cells from scratch. To do this, researchers combine tools from chemistry, materials science, and biochemistry to develop functional and structural building blocks to construct synthetic cell‐like systems. The many strategies and materials that have been developed in recent decades have enabled scientists to engineer synthetic cells and organelles that mimic the essential functions and behaviors of natural cells. Examples include synthetic cells that can synthesize their own ATP using light, maintain metabolic reactions through enzymatic networks, perform gene replication, and even grow and divide. In this Review, we discuss recent developments in the design and construction of synthetic cells and organelles using the bottom‐up approach. Our goal is to present representative synthetic cells of increasing complexity as well as strategies for solving distinct challenges in bottom‐up synthetic biology.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Synthetic Cells: From Simple Bio‐Inspired Modules to Sophisticated Integrated Systems ; day:30 ; month:03 ; year:2022 ; extent:21
Angewandte Chemie ; (30.03.2022) (gesamt 21)
- Urheber
- DOI
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10.1002/ange.202110855
- URN
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urn:nbn:de:101:1-2022033015191806345285
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 15.08.2025, 05:28 UTC
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Guindani, Camila
- Caire da Silva, Lucas
- Cao, Shoupeng
- Ivanov, Tsvetomir
- Landfester, Katharina
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