Primary intracranial choriocarcinoma presenting as a ring-enhancing lesion: A case report and review of literature
We report here a rare case of primary intracranial choriocarcinoma without evidence of tumor elsewhere, presenting as a ring-enhancing lesion managed successfully in our institute (Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India). A 22-year-old, right-handed housewife presented with complaints of headache, vomiting, generalized tonic–clonic seizures, and right upper limb weakness of short duration. On neurological examination, the patient was conscious, cooperative, well-oriented in time, place, and person. Visual acuity was 6/9 in both eyes. Fundus was showing grade 1 papilledema. Tone was increased on the right side. Power was decreased in the right upper limb as compared to the left. Reflexes were brisk in the right upper limb. Imaging was suggestive of a thick ring-enhancing lesion in the left parietal region suggestive of glioma or tuberculosis. Complete excision of the lesion was achieved. The diagnosis was confirmed by histopathologic examination of the lesion and β-human chorionic gonadotropin (β-HCG) levels. The patient recovered well postoperatively without neurological deficit. She was relieved of headache completely and there were no further episodes of vomiting or seizures. The right upper limb weakness improved to 4+/5. Choriocarcinoma is the most malignant lesion of all the gestational trophoblastic diseases. Primary brain choriocarcinoma presenting as a ring-enhancing lesion has not been reported in the literature. This diagnosis should be kept in mind, especially in young females of child-bearing age group. Complete surgical excision with adjunctive treatment is required to achieve prolonged remissions.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Primary intracranial choriocarcinoma presenting as a ring-enhancing lesion: A case report and review of literature ; volume:12 ; number:01 ; year:2017 ; pages:85-88
Asian journal of neurosurgery ; 12, Heft 01 (2017), 85-88
- Contributor
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Sharma, Mayur
Velho, Vernon
Binayake, Rachana
Tiwari, Chandranath
- DOI
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10.4103/1793-5482.145086
- URN
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urn:nbn:de:101:1-2022112412044558778700
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:29 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Sharma, Mayur
- Velho, Vernon
- Binayake, Rachana
- Tiwari, Chandranath
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Disseminated gestational choriocarcinoma presenting with hepatic and uveal metastases, hook effect, and choriocarcinoma syndrome
Neurosarcoidosis presenting as an incidental solitary cranial ring-enhancing lesion
An unusual biconvex epidural lesion: acutely presenting extraosseous intracranial Ewing’s sarcoma
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Thoracic splenosis presenting as pulmonary space-occupying lesion
Metastatic Intracranial Choriocarcinoma in the Absence of a Primary Lesion: A Case Report
Metastatic Choriocarcinoma Presenting as a Renal Mass:
Disseminated gestational choriocarcinoma presenting with hepatic and uveal metastases, hook effect, and choriocarcinoma syndrome
Neurosarcoidosis presenting as an incidental solitary cranial ring-enhancing lesion
An unusual biconvex epidural lesion: acutely presenting extraosseous intracranial Ewing’s sarcoma
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Electrocardiogram Changes in Intracranial Space Occupying Lesion
Brain Metastasis of a Primary Testicular Pure Choriocarcinoma Presenting with Frontal Lobe Hemorrhage
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Anorectal melanoma presenting as a polypoid lesion
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