Emerging Sonodynamic Therapy‐Based Nanomedicines for Cancer Immunotherapy
Abstract: Cancer immunotherapy effect can be greatly enhanced by other methods to induce immunogenic cell death (ICD), which has profoundly affected immunotherapy as a highly efficient paradigm. However, these treatments have significant limitations, either by causing damage of the immune system or limited to superficial tumors. Sonodynamic therapy (SDT) can induce ICD to promote immunotherapy without affecting the immune system because of its excellent spatiotemporal selectivity and low side effects. Nevertheless, SDT is still limited by low reactive oxygen species yield and the complex tumor microenvironment. Recently, some emerging SDT‐based nanomedicines have made numerous attractive and encouraging achievements in the field of cancer immunotherapy due to high immunotherapeutic efficiency. However, this cross‐cutting field of research is still far from being widely explored due to huge professional barriers. Herein, the characteristics of the tumor immune microenvironment and the mechanisms of ICD are firstly systematically summarized. Subsequently, the therapeutic mechanism of SDT is fully summarized, and the advantages and limitations of SDT are discussed. The representative advances of SDT‐based nanomedicines for cancer immunotherapy are further highlighted. Finally, the application prospects and challenges of SDT‐based immunotherapy in future clinical translation are discussed.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Emerging Sonodynamic Therapy‐Based Nanomedicines for Cancer Immunotherapy ; day:27 ; month:11 ; year:2022 ; extent:26
Advanced science ; (27.11.2022) (gesamt 26)
- Creator
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Yang, Yunrong
Huang, Jia
Liu, Min
Qiu, Yige
Chen, Qiaohui
Zhao, Tianjiao
Xiao, Zuoxiu
Yang, Yuqi
Jiang, Yitian
Huang, Qiong
Ai, Kelong
- DOI
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10.1002/advs.202204365
- URN
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urn:nbn:de:101:1-2022112814151260552518
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:26 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Yang, Yunrong
- Huang, Jia
- Liu, Min
- Qiu, Yige
- Chen, Qiaohui
- Zhao, Tianjiao
- Xiao, Zuoxiu
- Yang, Yuqi
- Jiang, Yitian
- Huang, Qiong
- Ai, Kelong
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