GQDs Incorporated CoPc Nanorods for Electrochemical Detection of Dopamine and Uric Acid
Abstract: Dopamine (DA) and uric acid (UA) are biomolecules of great consideration that coexist in human body. It is essential and challenging to detect them simultaneously with high sensitivity. This paper reports a novel electrochemical biosensor based on the nanocomposites of cobalt phthalocyanine (CoPc) anchored with graphene quantum dots (GQDs) for DA and UA detection. The GQDs incorporation on CoPc nanorods with partial end stretching significantly enhances the electrocatalytic activity and promotes the electron transfer rate. Low detection limits of 21 nm for DA and 145 nm for UA have been successfully achieved for the fabricated CoPc/GQDs biosensor. The density‐functional theory proves the enhanced conductivity of CoPc/GQDs and the biomolecule's interaction with the electrode surface. Furthermore, the proposed sensor shows remarkable reproducibility, repeatability, and stability. The fabricated sensor is applied for the simultaneous detections of DA and UA in human urine samples. The excellent performance suggests that the CoPc/GQDs could be a promising and potential candidate for electrochemical sensors to detect DA and UA selectively.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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GQDs Incorporated CoPc Nanorods for Electrochemical Detection of Dopamine and Uric Acid ; day:17 ; month:10 ; year:2022 ; extent:9
Advanced materials interfaces ; (17.10.2022) (gesamt 9)
- Urheber
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Wu, Bo
Li, Minzhang
Ramachandran, Rajendran
Niu, Gaoqiang
Zhang, Mingxiang
Zhao, Changhui
Xu, Zongxiang
Wang, Fei
- DOI
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10.1002/admi.202200738
- URN
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urn:nbn:de:101:1-2022101815023153751397
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:37 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Wu, Bo
- Li, Minzhang
- Ramachandran, Rajendran
- Niu, Gaoqiang
- Zhang, Mingxiang
- Zhao, Changhui
- Xu, Zongxiang
- Wang, Fei
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