An extra 1-cm margin during endoscopic submucosal dissection can control subsquamous tumor extension of the esophagogastric junction adenocarcinoma.
Background and study aims: Subsquamous tumor extension can occur in cases with esophagogastric junction adenocarcinomas, which makes accurate identification of the proximal tumor margin difficult and leads to incomplete tumor resection during endoscopic submucosal dissection. We prospectively elucidated the efficacy of including an extra 1-cm safety margin during dissection for achieving negative lateral margins. Patients and Methods: Patients with suspected esophagogastric junction adenocarcinomas participated in this single-center prospective feasibility study. Oral-side markings were placed 1 cm away from the endoscopic sign or 1 cm away from the squamous-columnar junction. The primary outcome was the complete resection rate. The secondary outcomes were the treatment outcomes and the incidence, length, and diagnostic rate of subsquamous tumor extension. Results: Twelve patients were assessed. The complete resection rate was 91.7% (11/12). All lesions were contained within the 1-cm safety margin. The incidence, median length, and diagnostic rate of subsquamous tumor extension was 75%, 5.7 mm (range: 1–24.8 mm), and 66.7%, respectively. Conclusions: An extra 1-cm safety margin is safe and helpful for achieving complete negative lateral margins during endoscopic submucosal dissection for esophagogastric junction adenocarcinomas. This margin is recommended to avoid residual cancers.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
An extra 1-cm margin during endoscopic submucosal dissection can control subsquamous tumor extension of the esophagogastric junction adenocarcinoma. ; day:05 ; month:09 ; year:2022
Endoscopy International Open ; (05.09.2022)
- Contributor
-
Manabe, Taku
Nagami, Yasuaki
TANOUE, KOJIRO
Sakai, Taishi
Maruyama, Hirotsugu
Ominami, Masaki
Fukunaga, Shusei
Otani, Koji
Hosomi, Shuhei
Tanaka, Fumio
Taira, Koichi
Watanabe, Toshio
Fujiwara, Yasuhiro
- DOI
-
10.1055/a-1936-9073
- URN
-
urn:nbn:de:101:1-2022111012383117074484
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:28 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Manabe, Taku
- Nagami, Yasuaki
- TANOUE, KOJIRO
- Sakai, Taishi
- Maruyama, Hirotsugu
- Ominami, Masaki
- Fukunaga, Shusei
- Otani, Koji
- Hosomi, Shuhei
- Tanaka, Fumio
- Taira, Koichi
- Watanabe, Toshio
- Fujiwara, Yasuhiro
Other Objects (12)
Clinical Efficacy of Endoscopic Submucosal Dissection for Adenocarcinomas of the Esophagogastric Junction
Novel therapeutic endoscope facilitates endoscopic submucosal dissection of adenocarcinoma at the esophagogastric junction
Giant atypical hyperplastic lesions on Barrett’s esophagus and at the esophagogastric junction resected by endoscopic submucosal dissection
The correlation between the margin of resection and prognosis in esophagogastric junction adenocarcinoma
Surgical options for submucosal tumors near the esophagogastric junction: does size or location matter?
Supplementary uses for a novel injecting needle-knife that facilitate esophagogastric endoscopic submucosal dissection
Salvage circumferential endoscopic submucosal dissection of multifocal Barrett’s adenocarcinoma at an esophagogastric anastomosis
Multiple snares-assisted endoscopic full-thickness resection of a giant submucosal tumor at the esophagogastric junction
Mediastinal lymph node dissection and distal esophagectomy is not essential in early esophagogastric junction adenocarcinoma
A retrospective analysis of lymph node dissection in Siewert II adenocarcinoma of the esophagogastric junction
Clinical outcomes of colorectal neoplasm with positive resection margin after endoscopic submucosal dissection
Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction
Clinical Efficacy of Endoscopic Submucosal Dissection for Adenocarcinomas of the Esophagogastric Junction
Novel therapeutic endoscope facilitates endoscopic submucosal dissection of adenocarcinoma at the esophagogastric junction
Giant atypical hyperplastic lesions on Barrett’s esophagus and at the esophagogastric junction resected by endoscopic submucosal dissection
The correlation between the margin of resection and prognosis in esophagogastric junction adenocarcinoma
Surgical options for submucosal tumors near the esophagogastric junction: does size or location matter?
Supplementary uses for a novel injecting needle-knife that facilitate esophagogastric endoscopic submucosal dissection
Salvage circumferential endoscopic submucosal dissection of multifocal Barrett’s adenocarcinoma at an esophagogastric anastomosis
Multiple snares-assisted endoscopic full-thickness resection of a giant submucosal tumor at the esophagogastric junction
Mediastinal lymph node dissection and distal esophagectomy is not essential in early esophagogastric junction adenocarcinoma
A retrospective analysis of lymph node dissection in Siewert II adenocarcinoma of the esophagogastric junction
Clinical outcomes of colorectal neoplasm with positive resection margin after endoscopic submucosal dissection
Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction
Clinical Efficacy of Endoscopic Submucosal Dissection for Adenocarcinomas of the Esophagogastric Junction
Novel therapeutic endoscope facilitates endoscopic submucosal dissection of adenocarcinoma at the esophagogastric junction
Giant atypical hyperplastic lesions on Barrett’s esophagus and at the esophagogastric junction resected by endoscopic submucosal dissection
The correlation between the margin of resection and prognosis in esophagogastric junction adenocarcinoma
Surgical options for submucosal tumors near the esophagogastric junction: does size or location matter?
Supplementary uses for a novel injecting needle-knife that facilitate esophagogastric endoscopic submucosal dissection
Salvage circumferential endoscopic submucosal dissection of multifocal Barrett’s adenocarcinoma at an esophagogastric anastomosis
Multiple snares-assisted endoscopic full-thickness resection of a giant submucosal tumor at the esophagogastric junction
Mediastinal lymph node dissection and distal esophagectomy is not essential in early esophagogastric junction adenocarcinoma
A retrospective analysis of lymph node dissection in Siewert II adenocarcinoma of the esophagogastric junction
Clinical outcomes of colorectal neoplasm with positive resection margin after endoscopic submucosal dissection