Characteristics and management of periprosthetic joint infections caused by rapidly growing mycobacteria: a retrospective study and a review of the literature

Abstract Background n = 6). The isolated RGM species included Mycobacterium abscessus (three cases), M. fortuitum (three cases), and one case each of M. immunogenum and M. mageritense. Surgical debridement was performed in all cases, with six patients undergoing two-stage revision and two patients requiring amputation. Combination antimicrobial therapy was administered based on antimicrobial susceptibility testing, and the median duration of treatment was 7.5 months. Adverse events related to therapy occurred in 75 % of cases. No relapses were observed during the median follow-up period of 39.6 months. Conclusions: PJI caused by RGM is a rare complication of total joint arthroplasty. Surgical debridement and combination antimicrobial therapy are the mainstays of treatment. Although clinical cure rates are high, amputation may be required in severe cases.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Characteristics and management of periprosthetic joint infections caused by rapidly growing mycobacteria: a retrospective study and a review of the literature ; volume:9 ; number:1 ; year:2024 ; pages:99-106 ; extent:8
Journal of bone and joint infection ; 9, Heft 1 (2024), 99-106 (gesamt 8)

Creator
Damronglerd, Pansachee
Higgins, Eibhlin
Fida, Madiha
Tai, Don Bambino Geno
Tande, Aaron J.
Abdel, Matthew P.
Abu Saleh, Omar M.

DOI
10.5194/jbji-9-99-2024
URN
urn:nbn:de:101:1-2024030703323815037995
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:56 AM CEST

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Associated

  • Damronglerd, Pansachee
  • Higgins, Eibhlin
  • Fida, Madiha
  • Tai, Don Bambino Geno
  • Tande, Aaron J.
  • Abdel, Matthew P.
  • Abu Saleh, Omar M.

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