Nanoparticles and the treatment of hepatocellular carcinoma

Abstract: Currently, liver cancer is the leading cause of cancer-related death worldwide, with a low 5-year survival rate, which will further decrease if advanced metastasis is present. Hepatocellular carcinoma (HCC) is the main type. However, due to the lack of specific symptoms in the early stages, it is more difficult to detect HCC, and many patients would have already been diagnosed with advanced liver cancer. At this point, many treatment methods available at early diagnosis would have become ineffective. Therefore, there is an urgent need for more effective treatment methods for HCC. In recent years, nanoparticles have been used in the treatment of HCC due to their good biocompatibility and other advantages. Different types of nanoparticles are modified to play a role in the treatment of HCC, such as regulating tumor microenvironment, enhancing the activity of drug targeting and killing cancer cells, and reducing systemic side effects. It can significantly improve the therapeutic effect of HCC and bring more hope for the treatment of HCC. In this review, several common nanoparticles are introduced, and their characteristics are described in detail. In addition, the construction of a highly efficient drug delivery system by nanoparticles and the combination of nanoparticle-targeted therapy, chemotherapy, and radiotherapy are reviewed.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Nanoparticles and the treatment of hepatocellular carcinoma ; volume:13 ; number:1 ; year:2024 ; extent:22
Nanotechnology reviews ; 13, Heft 1 (2024) (gesamt 22)

Creator
Zhang, Ziyu
Cao, Weihua
Li, Xinxin
Deng, Wen
Jiang, Tingting
Wang, Shiyu
Yang, Liu
Lin, Yanjie
Bi, Xiaoyue
Lu, Yao
Xu, Mengjiao
Zhang, Lu
Yi, Wei
Xie, Yao
Li, Minghui

DOI
10.1515/ntrev-2024-0134
URN
urn:nbn:de:101:1-2501021435526.653151108676
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:24 AM CEST

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Associated

  • Zhang, Ziyu
  • Cao, Weihua
  • Li, Xinxin
  • Deng, Wen
  • Jiang, Tingting
  • Wang, Shiyu
  • Yang, Liu
  • Lin, Yanjie
  • Bi, Xiaoyue
  • Lu, Yao
  • Xu, Mengjiao
  • Zhang, Lu
  • Yi, Wei
  • Xie, Yao
  • Li, Minghui

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