Stereoselective Biocatalyzed Reductions of Ginger Active Components Recovered from Industrial Wastes

Abstract: Ginger is among the most widespread and widely consumed traditional medicinal plants around the world. Its beneficial effects, which comprise e. g. anticancer and anti‐inflammatory activities as well as gastrointestinal regulatory effects, are generally attributed to a family of non‐volatile compounds characterized by an arylalkyl long‐chained alcohol, diol, or ketone moiety. In this work, ginger active components have been successfully recovered from industrial waste biomass of fermented ginger. Moreover, their recovery has been combined with the first systematic study of the stereoselective reduction of gingerol‐like compounds by isolated alcohol dehydrogenases (ADHs), obtaining the enantioenriched sec‐alcohol derivatives via a sustainable biocatalytic path in up to >99 % conversions and >99 % enantiomeric/diastereomeric excesses.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Stereoselective Biocatalyzed Reductions of Ginger Active Components Recovered from Industrial Wastes ; day:03 ; month:03 ; year:2022 ; extent:1
ChemBioChem ; (03.03.2022) (gesamt 1)

Creator
Nasti, Rita
Bassanini, Ivan
Ferrandi, Erica Elisa
Linguardo, Federica
Bertuletti, Susanna
Vanoni, Marta
Riva, Sergio
Verotta, Luisella
Monti, Daniela

DOI
10.1002/cbic.202200105
URN
urn:nbn:de:101:1-2022030414162979498175
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:26 AM CEST

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Associated

  • Nasti, Rita
  • Bassanini, Ivan
  • Ferrandi, Erica Elisa
  • Linguardo, Federica
  • Bertuletti, Susanna
  • Vanoni, Marta
  • Riva, Sergio
  • Verotta, Luisella
  • Monti, Daniela

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