Rhodococcus equi and Brucella pulmonary mass in immunocompetent: A case report and literature review

Abstract: Rhodococcus equi, predominantly recognized as an opportunistic pathogen affecting immunocompromised hosts, and Brucella, a widespread zoonotic bacterium, infrequently co-infect immunocompetent adults, thereby posing a distinctive diagnostic challenge. Here, we describe a case involving a 53-year-old male with a history of goat farming, who presented with persistent chest tightness, cough, and notable weight loss, absent fever. Radiological and bronchoscopic assessments showed a right hilar mass, extensive vertebral destruction, and bronchial lesions, deviating from the typical symptoms associated with either pathogen. Laboratory analyses confirmed a co-infection involving R. equi and Brucella. Initial therapy with levofloxacin and vancomycin proved ineffective; however, a subsequent treatment regimen comprising azithromycin, etimicin, minocycline, and moxifloxacin resulted in substantial clinical improvement. This case accentuates the intricacies involved in diagnosing and managing atypical co-infections in immunocompetent individuals and underscores the importance of careful microbiological testing to inform effective therapeutic strategies.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Rhodococcus equi and Brucella pulmonary mass in immunocompetent: A case report and literature review ; volume:19 ; number:1 ; year:2024 ; extent:6
Open life sciences ; 19, Heft 1 (2024) (gesamt 6)

Urheber
Li, Pengfei
Zhang, Lifang
Li, Xicheng
Zhang, Xuejuan

DOI
10.1515/biol-2022-0888
URN
urn:nbn:de:101:1-2406181538587.308081307029
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:57 MESZ

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Beteiligte

  • Li, Pengfei
  • Zhang, Lifang
  • Li, Xicheng
  • Zhang, Xuejuan

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