Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes

Abstract: The use of reactive gaseous reagents for the production of active pharmaceutical ingredients (APIs) remains a scientific challenge due to safety and efficiency limitations. The implementation of continuous‐flow reactors has resulted in rapid development of gas‐handling technology because of several advantages such as increased interfacial area, improved mass‐ and heat transfer, and seamless scale‐up. This technology enables shorter and more atom‐economic synthesis routes for the production of pharmaceutical compounds. Herein, we provide an overview of literature from 2016 onwards in the development of gas‐handling continuous‐flow technology as well as the use of gases in functionalization of APIs.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes ; day:27 ; month:12 ; year:2023 ; extent:29
Angewandte Chemie / International edition. International edition ; (27.12.2023) (gesamt 29)

Urheber
Laporte, Annechien A. H.
Masson, Tom M.
Zondag, Stefan D. A.
Noël, Timothy

DOI
10.1002/anie.202316108
URN
urn:nbn:de:101:1-2023122814212699423141
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:30 MESZ

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Beteiligte

  • Laporte, Annechien A. H.
  • Masson, Tom M.
  • Zondag, Stefan D. A.
  • Noël, Timothy

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