Multimodal analysis in symptomatic MIDD-associated retinopathy. A case report and literature review

Abstract: Purpose: To present results of contemporary multimodal ophthalmic imaging in a case of maternally inherited diabetes and deafness (MIDD) and a literature review of MIDD.Methods: A case of a 47-year-old female with diabetes mellitus, severe insulin resistance, familial lipodystrohy, deafness and increasing problems with vision is reported. A full ophthalmic examination was done, including best corrected visual acuity (BCVA, LogMAR), funduscopy, and imaging studies: optical coherence tomography (OCT), OCT angiography (OCT-A), fundus autofloresence (FAF), visual fields (HVF) 10-2 , electrophysiology (EP) and genetic testing were performed. Literature available on the topic was reviewed. Results: BCVA was 0.06 LogMAR in the right eye and 0.1 LogMAR in the left. Funduscopy revealed atrophy (AT) and pigmentary changes but no diabetic retinopathy. HVF confirmed corresponding defects.The imaging and diagnostic tests showed the following abnormalities: FAF: hypoautofluoresence in areas...

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Multimodal analysis in symptomatic MIDD-associated retinopathy. A case report and literature review ; volume:13 ; day:12 ; month:12 ; year:2023 ; GMS ophthalmology cases ; 13 (12.12.2023)

Classification and Topics

• Classification: Medizin, Gesundheit

Contributors, Places and Time

• Creator: Chwiejczak, Katarzyna ; Byles, Daniel ; Gerry, Paul ; Von, Lany Hirut ; Tasiopoulou, Anastasia ; Hattersley, Andrew

Further information

• DOI: 10.3205/oc000231
• URN: urn:nbn:de:0183-oc0002312
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 02.08.2025, 7:29 AM CEST