Krukenberg Tumor of Gastric Origin in Pregnant Women with Preeclampsia

Krukenberg tumor refers to a malignancy in the ovary that metastasizes from a primary site, classically the gastrointestinal tract. Pregnancy complicated with a Krukenberg tumor is very rare. In this report, we present two unusual cases of pregnant women with Krukenberg tumors of gastric origin. One case was a full-term pregnant woman with preeclampsia (PE) who underwent a caesarean section when bilateral enlarged ovaries were incidentally identified. Histopathology of the wedge resection biopsy showed single-ring cell carcinoma; this was followed by gastroscopy, which indicated a gastric origin. The woman received chemotherapy but died 6 months later. Another case was a pregnant woman at 30 gestational weeks with abdominal pain complicated with early-onset PE. Ultrasonography and magnetic resonance imaging showed bilateral enlarged ovaries and elevated tumor markers. Gastroscopy indicated linitis plastica. After an emergency caesarean section, adnexectomy was performed, and postoperative histopathology confirmed a Krukenberg tumor. The woman died 2 months after delivery. Gastrointestinal symptoms during pregnancy may indicate a malignancy of rare gastrointestinal origin. PE complicated with Krukenberg tumors in pregnancy should be considered in future studies.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Krukenberg Tumor of Gastric Origin in Pregnant Women with Preeclampsia ; volume:16 ; number:1 ; year:2023 ; pages:718-727 ; extent:10
Case reports in oncology ; 16, Heft 1 (2023), 718-727 (gesamt 10)

Creator
Zhang, Yongke
Du, Hui
Li, Taili
Li, Huan
Deng, Yuqing
Wu, Ruifang

DOI
10.1159/000531991
URN
urn:nbn:de:101:1-2023122723522654649464
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:23 AM CEST

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Associated

  • Zhang, Yongke
  • Du, Hui
  • Li, Taili
  • Li, Huan
  • Deng, Yuqing
  • Wu, Ruifang

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