Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report

Abstract: Introduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation: Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological examination showed metastasis of clear cell renal carcinoma. A thorough examination revealed a primary tumor on the lower pole of the right kidney. A right nephrectomy was performed, and histopathology showed ccRCC. Postoperative examinations showed no signs of local or systemic disease. Sunitinib malate was administered to the patient. Conclusion: The eyelid metastasis in this case was still solitary and had been discovered before the existence of the primary tumor was known. Ocular metastasis of renal carcinoma is a rare initial manifestation of the disease and therefore requires a multidisciplinary approach in the treatment of these patients.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report ; volume:17 ; number:1 ; year:2024 ; pages:477-483 ; extent:7 ; Case reports in oncology ; 17, Heft 1 (2024), 477-483 (gesamt 7)

Contributors, Places and Time

• Creator: Zrinšćak, Ognjen ; Kasumović, Armin ; Krolo, Iva ; Ivekovic, Renata ; Malenica Ravlić, Maja ; Tomašković, Igor ; Vatavuk, Zoran

Further information

• DOI: 10.1159/000537860
• URN: urn:nbn:de:101:1-2406270105400.379342898558
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:47 AM CEST