Dabigatran and warfarin in nonvalvular atrial fibrillation or atrial flutter in outpatient clinic practice in Brazil

Abstract: Objectives: To compare warfarin and dabigatran for thromboembolic event prevention in patients with nonvalvular atrial fibrillation or atrial flutter. Methods: This was a retrospective cohort of participants with nonvalvular atrial fibrillation or atrial flutter using either warfarin or dabigatran in a reference center in Brazil. Results: There were 112 patients (mean age 65.5 years), with 55.3% using warfarin. The median duration of follow-up was 1.9 years for warfarin and 1.6 years for dabigatran (p = 0.167). Warfarin patients had a higher median of medical appointments per year (8.3 [6.8-10.4] vs 3.1 [2.3-4.2], p < 0.001) and the frequency of minor bleeding was more than four times higher (17.7% vs 4.0%, p = 0.035). Among patients with prior stroke, those using warfarin had 2.6 times more medical appointments for person-years of follow-up (8.5 vs 3.3). There was no major bleeding or embolic event during follow-up period. Conclusion: The dabigatran group had a lower frequency of minor bleeding and number of medical appointments than the warfarin group, without more embolic events or major bleeding.

Object Details

• Alternative title: Dabigatrana e varfarina em pacientes com fibrilao atrial no valvar ou flutter em ambulatrio especializado no Brasil
• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Dabigatran and warfarin in nonvalvular atrial fibrillation or atrial flutter in outpatient clinic practice in Brazil ; volume:77 ; number:02 ; year:2019 ; pages:80-83 ; Arquivos de neuro-psiquiatria ; 77, Heft 02 (2019), 80-83

Contributors, Places and Time

• Contributor: Monteiro, Jean Michell Correia ; San-Martin, Daniel Lordelo ; Silva, Beatriz Carneiro Gondim ; Souza, Ian Felipe Barbosa ; Oliveira, Jamary ; Jesus, Pedro

Further information

• DOI: 10.1590/0004-282X20190005
• URN: urn:nbn:de:101:1-2023100512030746489520
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 11:01 AM CEST