Macromolecular Coatings for Endotracheal Tubes Probed on An Ex Vivo Extubation Setup
Abstract: Endotracheal intubation is indispensable in modern healthcare but typically entails two complications for the treated patients: biofouling‐induced infections and friction‐associated damage to the tissue. Coatings on the endotracheal tubes (ETT) may mitigate those problems, but they require a well‐defined testing method to assess their functionality. Here, such a testing setup is presented, which allows for conducting ex vivo extubation experiments in a reproducible manner. With this setup, different coating strategies that immobilize porcine gastric mucins on the ETT surface are compared. The results demonstrate that covalent coatings generated from lab‐purified mucins outperform the other variants in terms of their ability to decrease tissue damage, prevent lipid adsorption, and reduce cell attachment. With a similar approach as presented here, it should also be possible to evaluate macromolecular coatings generated on other medical tubing systems such as cardiac and urinary catheters and endoscopes.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Macromolecular Coatings for Endotracheal Tubes Probed on An Ex Vivo Extubation Setup ; day:04 ; month:12 ; year:2022 ; extent:10
Advanced materials interfaces ; (04.12.2022) (gesamt 10)
- Creator
- DOI
-
10.1002/admi.202201757
- URN
-
urn:nbn:de:101:1-2022120514021767767075
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:32 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Miller Naranjo, Bernardo
- Naicker, Semai
- Lieleg, Oliver
Other Objects (12)
The value of poly-urethane cuffed endotracheal tubes
Unterdrückung des Hustenreizes nach der Extubation durch endotracheal verabreichtes Lidocain 2%
Skin avulsion injury during endotracheal tube extubation – case report of an unusual complication
Biofilm formation on three different endotracheal tubes: a prospective clinical trial
Predicting feeding-tube dependence in patients following endotracheal extubation: a two-item swallowing screen
Prevention of ventilator-associated pneumonia by metal-coated endotracheal tubes: a meta-analysis
Real-time monitoring of Pseudomonas aeruginosa biofilm formation on endotracheal tubes in vitro
Comparison of nostril sizes of newborn infants with outer diameter of endotracheal tubes
Endotracheal tubes and fluid aspiration: an in vitro evaluation of new cuff technologies
The insecure airway: a comparison of knots and commercial devices for securing endotracheal tubes
Analysis of the current status of "pseudo" unplanned endotracheal extubation in ICU patients in China's tertiary hospitals
Endotracheal tubes with dexamethasone eluting electrospun coating improve tissue mechanical function after upper airway injury
The value of poly-urethane cuffed endotracheal tubes
Unterdrückung des Hustenreizes nach der Extubation durch endotracheal verabreichtes Lidocain 2%
Skin avulsion injury during endotracheal tube extubation – case report of an unusual complication
Biofilm formation on three different endotracheal tubes: a prospective clinical trial
Predicting feeding-tube dependence in patients following endotracheal extubation: a two-item swallowing screen
Prevention of ventilator-associated pneumonia by metal-coated endotracheal tubes: a meta-analysis
Real-time monitoring of Pseudomonas aeruginosa biofilm formation on endotracheal tubes in vitro
Comparison of nostril sizes of newborn infants with outer diameter of endotracheal tubes
Endotracheal tubes and fluid aspiration: an in vitro evaluation of new cuff technologies
The insecure airway: a comparison of knots and commercial devices for securing endotracheal tubes
Analysis of the current status of "pseudo" unplanned endotracheal extubation in ICU patients in China's tertiary hospitals
Endotracheal tubes with dexamethasone eluting electrospun coating improve tissue mechanical function after upper airway injury
The value of poly-urethane cuffed endotracheal tubes
Unterdrückung des Hustenreizes nach der Extubation durch endotracheal verabreichtes Lidocain 2%
Skin avulsion injury during endotracheal tube extubation – case report of an unusual complication
Biofilm formation on three different endotracheal tubes: a prospective clinical trial
Predicting feeding-tube dependence in patients following endotracheal extubation: a two-item swallowing screen
Prevention of ventilator-associated pneumonia by metal-coated endotracheal tubes: a meta-analysis
Real-time monitoring of Pseudomonas aeruginosa biofilm formation on endotracheal tubes in vitro
Comparison of nostril sizes of newborn infants with outer diameter of endotracheal tubes
Endotracheal tubes and fluid aspiration: an in vitro evaluation of new cuff technologies
The insecure airway: a comparison of knots and commercial devices for securing endotracheal tubes
Analysis of the current status of "pseudo" unplanned endotracheal extubation in ICU patients in China's tertiary hospitals