Is “Initial Size of the Graft the Real Culprit behind Primary Contraction of Full-Thickness Skin Graft”? – A Cross-Sectional Study

Abstract: Background Primary contraction of full-thickness graft has been traditionally quoted to be 40%. There are lacunae in literature to elaborate on the factors influencing it ever since. Methods About 75 subjects who underwent full-thickness grafting procedures to resurface small defects were included in the study. The initial and final graft dimensions after primary contraction were traced on X-ray templates and the percentage of contraction was evaluated using the graphical method. This was further correlated with age, collagen, elastic matrix metalloproteinases-1 (MMP-1) and -2 content along with dermal thickness of the skin specimen sent from the graft. Results The primary contraction of the graft had a very significant correlation only with the initial size of graft harvested with a linear regression of 33.3% and a Spearman's correlation of 0.587 significant at a p-value of 0.001. Conclusion This study though preliminary tries to highlight an important factor that primary contraction of grafts is a physical phenomenon independent of its contents like collagen, elastin, or MMP-1 and -2 or age and dependent on its initial size of harvest instead.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Is “Initial Size of the Graft the Real Culprit behind Primary Contraction of Full-Thickness Skin Graft”? – A Cross-Sectional Study ; volume:50 ; number:01 ; year:2023 ; pages:106-115
Archives of Plastic Surgery ; 50, Heft 01 (2023), 106-115

Beteiligte Personen und Organisationen
Vathulya, Madhubari
Rao, Shalinee
Malik, Akanksha
Sinha, Smita
Kumar, Nikhilesh
Kapoor, Akshay
Bahurupi, Yogesh

DOI
10.1055/s-0042-1756297
URN
urn:nbn:de:101:1-2023033010435616830002
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:45 MESZ

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Beteiligte

  • Vathulya, Madhubari
  • Rao, Shalinee
  • Malik, Akanksha
  • Sinha, Smita
  • Kumar, Nikhilesh
  • Kapoor, Akshay
  • Bahurupi, Yogesh

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