In-Silico discovery of 17alpha-hydroxywithanolide-D as potential neuroprotective allosteric modulator of NMDA receptor targeting Alzheimer’s disease

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: 1 Online-Ressource.

Language: Englisch

Bibliographic citation: In-Silico discovery of 17alpha-hydroxywithanolide-D as potential neuroprotective allosteric modulator of NMDA receptor targeting Alzheimer’s disease ; volume:14 ; number:1 ; day:13 ; month:11 ; year:2024 ; pages:1-19 ; date:12.2024
Scientific reports ; 14, Heft 1 (13.11.2024), 1-19, 12.2024

Creator: Vashisth, Manoj Kumar
Hu, Junkai
Liu, Mingrui
Basha, Syed Hussain
Yu, Chen
Huang, Wenhua

Contributor: SpringerLink (Online service)

DOI: 10.1038/s41598-024-78975-2

URN: urn:nbn:de:101:1-2502040922202.546333742024

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:36 AM CEST

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Vashisth, Manoj Kumar
Hu, Junkai
Liu, Mingrui
Basha, Syed Hussain
Yu, Chen
Huang, Wenhua
SpringerLink (Online service)

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In-Silico discovery of 17alpha-hydroxywithanolide-D as potential neuroprotective allosteric modulator of NMDA receptor targeting Alzheimer’s disease

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Other Objects (12)

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The molecular mechanisms of Abyssinone-I protect against Alzheimer’s disease: an in-silico study

Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer’s disease

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis

Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease

Biaryl scaffold-focused virtual screening for anti-aggregatory and neuroprotective effects in Alzheimer’s disease

Molecular characterization of neuroprotective β-amyloid interacting peptides and autoantibodies relevant to Alzheimer’s disease

Evaluating the neuroprotective effect of Spirulina platensis–loaded niosomes against Alzheimer’s disease induced in rats

Assessment of neuroprotective effects of gamma-hydroxybutyrate and neurosteroids on cellular models of Alzheimer’s disease

Identification of AChE targeted therapeutic compounds for Alzheimer’s disease: an in-silico study with DFT integration

Dysfunction of NMDA receptors in Alzheimer’s disease

Enhancing mitochondrial one-carbon metabolism is neuroprotective in Alzheimer’s disease models

Molecular mechanisms of sulforaphane in Alzheimer’s disease: insights from an in-silico study

The molecular mechanisms of Abyssinone-I protect against Alzheimer’s disease: an in-silico study

Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer’s disease

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis

Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease

Biaryl scaffold-focused virtual screening for anti-aggregatory and neuroprotective effects in Alzheimer’s disease

Molecular characterization of neuroprotective β-amyloid interacting peptides and autoantibodies relevant to Alzheimer’s disease

Evaluating the neuroprotective effect of Spirulina platensis–loaded niosomes against Alzheimer’s disease induced in rats

Assessment of neuroprotective effects of gamma-hydroxybutyrate and neurosteroids on cellular models of Alzheimer’s disease

Identification of AChE targeted therapeutic compounds for Alzheimer’s disease: an in-silico study with DFT integration

Dysfunction of NMDA receptors in Alzheimer’s disease

Enhancing mitochondrial one-carbon metabolism is neuroprotective in Alzheimer’s disease models

Molecular mechanisms of sulforaphane in Alzheimer’s disease: insights from an in-silico study

The molecular mechanisms of Abyssinone-I protect against Alzheimer’s disease: an in-silico study

Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer’s disease

Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis

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Biaryl scaffold-focused virtual screening for anti-aggregatory and neuroprotective effects in Alzheimer’s disease

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