CRISPR memories in single cells

CRISPR‐Cas systems allow bacteria to memorize prior infections as a means to combat the same invader if it attempts another attack in the future. While the underlying mechanisms of this bacterial immunity have been intensely studied over the past decade, little attention has been paid to CRISPR defense at the single‐cell level. In their recent work, Brouns and colleagues (McKenzie et al, 2022) track memory acquisition and defense in individual cells and find a wide range of temporal dynamics that shape how a cell population experiences and combats an active infection.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
CRISPR memories in single cells ; volume:18 ; number:4 ; year:2022 ; extent:2
Molecular systems biology ; 18, Heft 4 (2022) (gesamt 2)

Creator
Sparmann, Anke
Beisel, Chase L.

DOI
10.15252/msb.202211011
URN
urn:nbn:de:101:1-2022042515173825768667
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:26 AM CEST

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Associated

  • Sparmann, Anke
  • Beisel, Chase L.

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