Administration of Different Catecholamines and Prostaglandin Endoperoxide Formation in Thrombocytes
In patients following myocardial infarction and patients sufferingfrom circulatory shock soluble fibrin in plasma is often elevated as a sign of an activated plasmatic coagulation system. Soluble fibrin is moat pronounced in patients under catecholamine administration. These patients also show an accelerated production of prostaglandin-endoperoxides in thrombocytes indicating concomitant platelet activation. Soluble fibrin was quantified by affinity chromatography and proetaglam-din-endoperoxides were measured after incubation with N-ethylmaleimide as n moles raalondialdehyde. To elucidate the prostaglandin-endoperoxide promoting effect in platelets of epinephrine, norepinephrine and dopamine-these substances are often used to sustain blood pressure and to improve circulation -, the catecholamines were added to platelet rich plasma as well as infused into rabbits. Epinephrine and norepinephrine stimulate prostaglandin-endoperoxide production; in contrast to that dopamine has no effect on platelet endoperoxide formation. This phenomenon may be of favor to avoid at least partly drug induced hypercoagulability and consumption coagulopathy so far as platelet pro-coagulant activities are involved.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Administration of Different Catecholamines and Prostaglandin Endoperoxide Formation in Thrombocytes ; volume:42 ; number:06 ; year:1979
Konferenz: VIIth International Congress on Thrombosis and Haemostasis; 1979-07-15; London
Thrombosis and haemostasis ; 42, Heft 06 (1979)
- Contributor
-
Matthias, F.R.
Palinski, W.
- DOI
-
10.1055/s-0039-1687565
- URN
-
urn:nbn:de:101:1-2412190901595.252815957535
- Rights
-
Open Access unbekannt; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:27 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Matthias, F.R.
- Palinski, W.
Other Objects (12)
Platelet Prostaglandin Endoperoxides Formation in Hyperlipidemias
Effects of prostaglandin E1 on callus formation in rabbits
![Die klinische Anwendung von Prostaglandin-F2α [Prostaglandin-F-alpha], Prostaglandin-E2 [Prostaglandin-E] und 15-Methyl-Prostaglandin-F2α [Methyl-Prostaglandin-F-alpha] bei schwangeren Frauen](/assets/placeholder/searchResultMediaNoDigitisedMedia.png)
Die klinische Anwendung von Prostaglandin-F2α [Prostaglandin-F-alpha], Prostaglandin-E2 [Prostaglandin-E] und 15-Methyl-Prostaglandin-F2α [Methyl-Prostaglandin-F-alpha] bei schwangeren Frauen
Myeloid Cells and Sensory Nerves Mediate Peritendinous Adhesion Formation via Prostaglandin E2
Die Regulation der Prostaglandin E1-Synthese [Prostaglandin-E-Synthese] und Prostaglandin E1-Empfindlichkeit [Prostaglandin-E-Empfindlichkeit] von Phagozyten
Anti-inflammatory effects of the prostaglandin D2/prostaglandin DP1 receptor and lipocalin-type prostaglandin D2 synthase/prostaglandin D2 pathways in bacteria-induced bovine endometrial tissue
Prostaglandin and prostaglandin receptors: present and future promising therapeutic targets for pulmonary arterial hypertension
Prostaglandin-E2- [Prostaglandin-E-] und Prostaglandin-F2a-Konzentrationen [Prostaglandin-Fa-Konzentrationen] in Rückenmarks- und Hypophysentumoren und deren Freisetzung in den Liquor cerebrospinalis
Resveratrol potently reduces prostaglandin E2production and free radical formation in lipopolysaccharide-activated primary rat microglia
Prostaglandin E2 [E], Prostaglandin F2α [F-alpha], 6-Keto-Prostaglandin [Keto-Prostaglandin] F1α [F-alpha] und Thromboxan B2 [B] bei chronisch leberkranken Patienten
Glycogenolytic and antiglycogenolytic prostaglandin E₂ actions in rat hepatocytes are mediated via different signalling pathways
Resveratrol inhibits prostaglandin formation in IL-1β-stimulated SK-N-SH neuronal cells
Platelet Prostaglandin Endoperoxides Formation in Hyperlipidemias
Effects of prostaglandin E1 on callus formation in rabbits
Die klinische Anwendung von Prostaglandin-F2α [Prostaglandin-F-alpha], Prostaglandin-E2 [Prostaglandin-E] und 15-Methyl-Prostaglandin-F2α [Methyl-Prostaglandin-F-alpha] bei schwangeren Frauen
Myeloid Cells and Sensory Nerves Mediate Peritendinous Adhesion Formation via Prostaglandin E2
Die Regulation der Prostaglandin E1-Synthese [Prostaglandin-E-Synthese] und Prostaglandin E1-Empfindlichkeit [Prostaglandin-E-Empfindlichkeit] von Phagozyten
Anti-inflammatory effects of the prostaglandin D2/prostaglandin DP1 receptor and lipocalin-type prostaglandin D2 synthase/prostaglandin D2 pathways in bacteria-induced bovine endometrial tissue
Prostaglandin and prostaglandin receptors: present and future promising therapeutic targets for pulmonary arterial hypertension
Prostaglandin-E2- [Prostaglandin-E-] und Prostaglandin-F2a-Konzentrationen [Prostaglandin-Fa-Konzentrationen] in Rückenmarks- und Hypophysentumoren und deren Freisetzung in den Liquor cerebrospinalis
Resveratrol potently reduces prostaglandin E2production and free radical formation in lipopolysaccharide-activated primary rat microglia
Prostaglandin E2 [E], Prostaglandin F2α [F-alpha], 6-Keto-Prostaglandin [Keto-Prostaglandin] F1α [F-alpha] und Thromboxan B2 [B] bei chronisch leberkranken Patienten
Glycogenolytic and antiglycogenolytic prostaglandin E₂ actions in rat hepatocytes are mediated via different signalling pathways
Resveratrol inhibits prostaglandin formation in IL-1β-stimulated SK-N-SH neuronal cells
Platelet Prostaglandin Endoperoxides Formation in Hyperlipidemias
Effects of prostaglandin E1 on callus formation in rabbits
Die klinische Anwendung von Prostaglandin-F2α [Prostaglandin-F-alpha], Prostaglandin-E2 [Prostaglandin-E] und 15-Methyl-Prostaglandin-F2α [Methyl-Prostaglandin-F-alpha] bei schwangeren Frauen
Myeloid Cells and Sensory Nerves Mediate Peritendinous Adhesion Formation via Prostaglandin E2
Die Regulation der Prostaglandin E1-Synthese [Prostaglandin-E-Synthese] und Prostaglandin E1-Empfindlichkeit [Prostaglandin-E-Empfindlichkeit] von Phagozyten
Anti-inflammatory effects of the prostaglandin D2/prostaglandin DP1 receptor and lipocalin-type prostaglandin D2 synthase/prostaglandin D2 pathways in bacteria-induced bovine endometrial tissue
Prostaglandin and prostaglandin receptors: present and future promising therapeutic targets for pulmonary arterial hypertension
Prostaglandin-E2- [Prostaglandin-E-] und Prostaglandin-F2a-Konzentrationen [Prostaglandin-Fa-Konzentrationen] in Rückenmarks- und Hypophysentumoren und deren Freisetzung in den Liquor cerebrospinalis
Resveratrol potently reduces prostaglandin E2production and free radical formation in lipopolysaccharide-activated primary rat microglia
Prostaglandin E2 [E], Prostaglandin F2α [F-alpha], 6-Keto-Prostaglandin [Keto-Prostaglandin] F1α [F-alpha] und Thromboxan B2 [B] bei chronisch leberkranken Patienten
Glycogenolytic and antiglycogenolytic prostaglandin E₂ actions in rat hepatocytes are mediated via different signalling pathways