Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase ; day:09 ; month:11 ; year:2022 ; extent:1
ChemBioChem ; (09.11.2022) (gesamt 1)

Creator: Battisti, Umberto Maria
Gao, Chunxia
Nilsson, Oscar
Akladios, Fady
Lulla, Aleksei
Bogucka, Agnieszka
Nain‐Perez, Amalyn
Håversen, Liliana
Kim, Woonghee
Boren, Jan
Hyvönen, Marko
Uhlen, Mathias
Mardinoglu, Adil
Grøtli, Morten

DOI: 10.1002/cbic.202200339

URN: urn:nbn:de:101:1-2022111014091218938574

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:25 AM CEST

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Associated

Battisti, Umberto Maria
Gao, Chunxia
Nilsson, Oscar
Akladios, Fady
Lulla, Aleksei
Bogucka, Agnieszka
Nain‐Perez, Amalyn
Håversen, Liliana
Kim, Woonghee
Boren, Jan
Hyvönen, Marko
Uhlen, Mathias
Mardinoglu, Adil
Grøtli, Morten

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Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

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Other Objects (12)

Structure‐Based Design of AG‐946, a Pyruvate Kinase Activator

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Protein kinase function of pyruvate kinase M2 and cancer

Role of Myeloid Pyruvate Kinase Isoform M2 (PKM2) in Homeostasis and Acute Liver Inflammation

Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate kinase deficiency natural history study

Pyruvate kinase expression and activity in hearts, kidneys and livers of mice with streptozotocin-induced diabetes

Upregulation of pyruvate dehydrogenase kinase 4 enhances hepatocyte chemoprotection

Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Phosphorylation is switch of L-type pyruvate kinase allostery

Psychometric validation of the Pyruvate Kinase Deficiency Diary and Pyruvate Kinase Deficiency Impact Assessment in adults in the phase 3 ACTIVATE trial

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On the role of pyruvate kinase M2 in tumor metabolism

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Pyruvate kinase in human amniotic fluid

Protein kinase function of pyruvate kinase M2 and cancer

Role of Myeloid Pyruvate Kinase Isoform M2 (PKM2) in Homeostasis and Acute Liver Inflammation

Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate kinase deficiency natural history study

Pyruvate kinase expression and activity in hearts, kidneys and livers of mice with streptozotocin-induced diabetes

Upregulation of pyruvate dehydrogenase kinase 4 enhances hepatocyte chemoprotection

Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Phosphorylation is switch of L-type pyruvate kinase allostery

Psychometric validation of the Pyruvate Kinase Deficiency Diary and Pyruvate Kinase Deficiency Impact Assessment in adults in the phase 3 ACTIVATE trial

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On the role of pyruvate kinase M2 in tumor metabolism

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Pyruvate kinase in human amniotic fluid

Protein kinase function of pyruvate kinase M2 and cancer

Role of Myeloid Pyruvate Kinase Isoform M2 (PKM2) in Homeostasis and Acute Liver Inflammation

Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate kinase deficiency natural history study

Pyruvate kinase expression and activity in hearts, kidneys and livers of mice with streptozotocin-induced diabetes

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Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

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