Advanced preclinical CRISPR mouse models to explore context-dependent effects of TP53 mutations in cancer

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Notes: Marburg, Philipps-Universität Marburg, Dissertation, 2023

Event: Veröffentlichung

(where): Marburg

(who): Philipps-Universität Marburg

(when): 2023

Creator: Merle, Nastasja

Contributor: Stiewe, Thorsten

DOI: 10.17192/z2023.0178

URN: urn:nbn:de:hebis:04-z2023-01780

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 25.03.2025, 1:51 PM CET

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Associated

Merle, Nastasja
Stiewe, Thorsten
Philipps-Universität Marburg

Time of origin

2023

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Advanced preclinical CRISPR mouse models to explore context-dependent effects of TP53 mutations in cancer

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Other Objects (12)

Functional classification of TP53 mutations in acute myeloid leukemia

Functional characterization of the TP53 mutome using CRISPR/Cas9 saturating mutagenesis

Prognostic and predictive value of TP53 mutations in pediatric medulloblastoma

Response to "Unexpected mutations after CRISPR–Cas9 editing in vivo"

Gene mutations and losses of heterozygosity of TP53 and PTEN in colorectal cancer

Gene mutations and losses of heterozygosity of TP53 and PTEN in colorectal cancer

TP53 and SF3B1 mutations in pituitary tumours : unravelling molecular drivers of aggressive tumour behaviour

Clinical characterization and prognostic impact of SF3B1 and TP53 gene mutations in myelodysplastic syndromes

TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance

Identification and inactivation of cancer driver mutations using the CRISPR-Cas9 system

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia

First-line immunotherapy for lung cancer with MET exon 14 skipping and the relevance of TP53 mutations

Functional classification of TP53 mutations in acute myeloid leukemia

Functional characterization of the TP53 mutome using CRISPR/Cas9 saturating mutagenesis

Prognostic and predictive value of TP53 mutations in pediatric medulloblastoma

Response to "Unexpected mutations after CRISPR–Cas9 editing in vivo"

Gene mutations and losses of heterozygosity of TP53 and PTEN in colorectal cancer

Gene mutations and losses of heterozygosity of TP53 and PTEN in colorectal cancer

TP53 and SF3B1 mutations in pituitary tumours : unravelling molecular drivers of aggressive tumour behaviour

Clinical characterization and prognostic impact of SF3B1 and TP53 gene mutations in myelodysplastic syndromes

TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance

Identification and inactivation of cancer driver mutations using the CRISPR-Cas9 system

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia

First-line immunotherapy for lung cancer with MET exon 14 skipping and the relevance of TP53 mutations

Functional classification of TP53 mutations in acute myeloid leukemia

Functional characterization of the TP53 mutome using CRISPR/Cas9 saturating mutagenesis

Prognostic and predictive value of TP53 mutations in pediatric medulloblastoma

Response to "Unexpected mutations after CRISPR–Cas9 editing in vivo"

Gene mutations and losses of heterozygosity of TP53 and PTEN in colorectal cancer

Gene mutations and losses of heterozygosity of TP53 and PTEN in colorectal cancer

TP53 and SF3B1 mutations in pituitary tumours : unravelling molecular drivers of aggressive tumour behaviour

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TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance

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