Synthesis and antimicrobial assessment of new substituted 10 H -phenothiazines, their sulfone derivatives, and ribofuranosides

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Abstract: A series of new 10H-phenothiazines, their sulfones, and ribofuranosides were synthesized and their in vitro antimicrobial assessment was carried out against a representative panel of Gram-positive and Gram-negative bacterial strains and selected fungi species. The 10H-phenothiazines were prepared using Smiles rearrangement. The sulfone derivatives were synthesized by oxidation of 10H-phenothiazines using 30% hydrogen peroxide in glacial acetic acid. The ribofuranosides were prepared by treatment of the phenothiazines with β-d-ribofuranosyl-1-acetate-2,3,5-tribenzoate.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Synthesis and antimicrobial assessment of new substituted 10 H -phenothiazines, their sulfone derivatives, and ribofuranosides ; volume:20 ; number:6 ; year:2014 ; pages:343-349 ; extent:7
Heterocyclic communications ; 20, Heft 6 (2014), 343-349 (gesamt 7)

Creator: Gautam, Naveen
Garg, Ankita
Lal, Thandi
Gautam, Dinesh Chand
Joshi, Jyoti

DOI: 10.1515/hc-2014-0087

URN: urn:nbn:de:101:1-2501130540082.079233483871

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:24 AM CEST

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Gautam, Naveen
Garg, Ankita
Lal, Thandi
Gautam, Dinesh Chand
Joshi, Jyoti

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Synthesis and antimicrobial assessment of new substituted 10 H -phenothiazines, their sulfone derivatives, and ribofuranosides

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