Genetic alterations in lymphoblastic leukaemia  /lymphoma – a practical guide to WHO HAEM5

Abstract: We present a practical guide for analyzing the genetic aspects of lymphoblastic leukaemia/lymphoma according to the 5th edition of the World Health Organization (WHO) classification of haematolymphoid neoplasms (WHO-HAEM5) issued in 2024. The WHO-HAEM5 acknowledges the increasing importance of genetics in the diagnosis of lymphoid neoplasia. Classification is based on the established genetic subtypes according to cell lineage, with precursor cell neoplasms followed by mature malignancies. This guide describes those genetic abnormalities in acute precursor B- and T-cell neoplasms required for risk stratification, and for treatment, providing diagnostic algorithms under the headings of ‘essential’ and ‘desirable’ diagnostic criteria.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Genetic alterations in lymphoblastic leukaemia /lymphoma – a practical guide to WHO HAEM5 ; volume:36 ; number:1 ; year:2024 ; pages:39-45 ; extent:7 ; Medizinische Genetik ; 36, Heft 1 (2024), 39-45 (gesamt 7)

Contributors, Places and Time

• Creator: Steinemann, Doris ; Dawidowska, Małgorzata ; Russell, Lisa J. ; Harrison, Christine J. ; Göhring, Gudrun

Further information

• DOI: 10.1515/medgen-2024-2007
• URN: urn:nbn:de:101:1-2024030613560730649259
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:53 AM CEST