Towards model‐guided feedback control of hydrogels bioprinting
Abstract: This contribution addresses the problem of controlling the Degree of Crosslinking (DoC) in printed hydrogels through feedback control as a product quality indicator from a modeling approach. We set up a simulation that resembles co‐axial printing of calcium‐alginate (Ca‐Alg) hydrogel as a case study. A well‐known Ca‐Alg gelation model composed of a set of nonlinear coupled diffusion‐reactions equations is adopted as a high‐fidelity model (HFM). A traditional proportional‐integral (PI) controller is designed based on a reduced‐order state‐space linear model of the gelation process. The linear state‐space model is identified from input‐output data collected from the HFM. We formulate an optimization problem to find optimal PI controller parameters that minimize a closed‐loop performance index. The PI controller is directly applied to the nonlinear diffusion‐reaction model to guide the printing process towards a desired DoC. We show its efficacy via some numerical simulations.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Towards model‐guided feedback control of hydrogels bioprinting ; day:27 ; month:09 ; year:2024 ; extent:12
Proceedings in applied mathematics and mechanics ; (27.09.2024) (gesamt 12)
- Urheber
- DOI
-
10.1002/pamm.202400026
- URN
-
urn:nbn:de:101:1-2409271414264.659979929150
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:35 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Urrea‐Quintero, Jorge‐Humberto
- Wessels, Henning
- Wick, Thomas
Ähnliche Objekte (12)
Granular Biphasic Colloidal Hydrogels for 3D Bioprinting
Nanomaterials-incorporated hydrogels for 3D bioprinting technology
Evaluation of hydrogels based on oxidized hyaluronic acid for bioprinting
Tuning Superfast Curing Thiol‐Norbornene‐Functionalized Gelatin Hydrogels for 3D Bioprinting
Multi-length scale bioprinting towards simulating microenvironmental cues
Fine‐tuning Dynamic Cross–linking for Enhanced 3D Bioprinting of Hyaluronic Acid Hydrogels
Thiol-ene Cross-linked Poly(glycidol) / Hyaluronic Acid Based Hydrogels for 3D Bioprinting
Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms
NK cells encapsulated in micro/macropore-forming hydrogels via 3D bioprinting for tumor immunotherapy
Engineering Conductive Hydrogels with Tissue‐like Properties: A 3D Bioprinting and Enzymatic Polymerization Approach
Bioprinting of Cell‐Laden Hydrogels onto Titanium Alloy Surfaces to Produce a Bioactive Interface
Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver‐Like Metabolic Biofactories
Granular Biphasic Colloidal Hydrogels for 3D Bioprinting
Nanomaterials-incorporated hydrogels for 3D bioprinting technology
Evaluation of hydrogels based on oxidized hyaluronic acid for bioprinting
Tuning Superfast Curing Thiol‐Norbornene‐Functionalized Gelatin Hydrogels for 3D Bioprinting
Multi-length scale bioprinting towards simulating microenvironmental cues
Fine‐tuning Dynamic Cross–linking for Enhanced 3D Bioprinting of Hyaluronic Acid Hydrogels
Thiol-ene Cross-linked Poly(glycidol) / Hyaluronic Acid Based Hydrogels for 3D Bioprinting
Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms
NK cells encapsulated in micro/macropore-forming hydrogels via 3D bioprinting for tumor immunotherapy
Engineering Conductive Hydrogels with Tissue‐like Properties: A 3D Bioprinting and Enzymatic Polymerization Approach
Bioprinting of Cell‐Laden Hydrogels onto Titanium Alloy Surfaces to Produce a Bioactive Interface
Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver‐Like Metabolic Biofactories
Granular Biphasic Colloidal Hydrogels for 3D Bioprinting
Nanomaterials-incorporated hydrogels for 3D bioprinting technology
Evaluation of hydrogels based on oxidized hyaluronic acid for bioprinting
Tuning Superfast Curing Thiol‐Norbornene‐Functionalized Gelatin Hydrogels for 3D Bioprinting
Multi-length scale bioprinting towards simulating microenvironmental cues
Fine‐tuning Dynamic Cross–linking for Enhanced 3D Bioprinting of Hyaluronic Acid Hydrogels
Thiol-ene Cross-linked Poly(glycidol) / Hyaluronic Acid Based Hydrogels for 3D Bioprinting
Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms
NK cells encapsulated in micro/macropore-forming hydrogels via 3D bioprinting for tumor immunotherapy
Engineering Conductive Hydrogels with Tissue‐like Properties: A 3D Bioprinting and Enzymatic Polymerization Approach
Bioprinting of Cell‐Laden Hydrogels onto Titanium Alloy Surfaces to Produce a Bioactive Interface