Implementing the ESMO recommendations for the use of circulating tumor DNA (ctDNA) assays in routine clinical application/diagnostics

Abstract: Liquid biopsy (LB) represents an advanced, minimally invasive approach that elevates the precision of oncological decision-making by identifying tumor DNA in bodily fluids. However, despite numerous endorsements from international specialty societies and working groups, implementation of LB into routine care is lagging behind due to conceptual and methodological uncertainties. This concise mini review aims to help catalyzing the translation of LB into routine care by exploring key considerations for incorporating circulating tumor DNA (ctDNA) analysis into clinical practice. Addressing eight pertinent questions from the perspective of a molecular oncology laboratory, this review synthesizes insights from the European Society for Medical Oncology (ESMO) recommendations and incorporates the latest findings from relevant literature, offering a comprehensive guide to the implementation of ctDNA assays.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Implementing the ESMO recommendations for the use of circulating tumor DNA (ctDNA) assays in routine clinical application/diagnostics ; volume:48 ; number:4 ; year:2024 ; pages:141-151 ; extent:11
Journal of laboratory medicine ; 48, Heft 4 (2024), 141-151 (gesamt 11)

Creator
Gamisch, Alexander
Mustafa, Hans Georg
Haushofer, Alexander
Mustafa-Korninger, Maria-Elisabeth

DOI
10.1515/labmed-2024-0029
URN
urn:nbn:de:101:1-2408101552297.063411063243
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:45 AM CEST

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Associated

  • Gamisch, Alexander
  • Mustafa, Hans Georg
  • Haushofer, Alexander
  • Mustafa-Korninger, Maria-Elisabeth

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