The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
1 Online-Ressource.
- Sprache
-
Englisch
- Erschienen in
-
The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons ; volume:15 ; number:1 ; day:19 ; month:6 ; year:2024 ; pages:1-17 ; date:12.2024
Nature Communications ; 15, Heft 1 (19.6.2024), 1-17, 12.2024
- Urheber
-
Wani, Willayat Y.
Zunke, Friederike
Belur, Nandkishore R.
Mazzulli, Joseph R.
- Beteiligte Personen und Organisationen
-
SpringerLink (Online service)
- DOI
-
10.1038/s41467-024-49256-3
- URN
-
urn:nbn:de:101:1-2409110944283.379320406675
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:33 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Wani, Willayat Y.
- Zunke, Friederike
- Belur, Nandkishore R.
- Mazzulli, Joseph R.
- SpringerLink (Online service)
Ähnliche Objekte (12)
Modeling Parkinson’s disease in midbrain-like organoids
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons
Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson’s disease
Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
Lysosomal Pathogenesis of Parkinson’s Disease: Insights From LRRK2 and GBA1 Rodent Models
Human midbrain organoids: a powerful tool for advanced Parkinson’s disease modeling and therapy exploration
Lysosomal genes contribute to Parkinson’s disease near agriculture with high intensity pesticide use
The reciprocal influence of alpha-synuclein aggregation and lysosomal homeostasis in Parkinson’s disease
Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons
Modeling Parkinson’s disease in midbrain-like organoids
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons
Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson’s disease
Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
Lysosomal Pathogenesis of Parkinson’s Disease: Insights From LRRK2 and GBA1 Rodent Models
Human midbrain organoids: a powerful tool for advanced Parkinson’s disease modeling and therapy exploration
Lysosomal genes contribute to Parkinson’s disease near agriculture with high intensity pesticide use
The reciprocal influence of alpha-synuclein aggregation and lysosomal homeostasis in Parkinson’s disease
Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons
Modeling Parkinson’s disease in midbrain-like organoids
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons
Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson’s disease
Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
Lysosomal Pathogenesis of Parkinson’s Disease: Insights From LRRK2 and GBA1 Rodent Models
Human midbrain organoids: a powerful tool for advanced Parkinson’s disease modeling and therapy exploration
Lysosomal genes contribute to Parkinson’s disease near agriculture with high intensity pesticide use
The reciprocal influence of alpha-synuclein aggregation and lysosomal homeostasis in Parkinson’s disease