Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- ISSN
-
2045-2322
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Anmerkungen
-
online resource.
- Erschienen in
-
Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment ; volume:12 ; number:1 ; day:9 ; month:11 ; year:2022 ; pages:1-7 ; date:12.2022
Scientific reports ; 12, Heft 1 (9.11.2022), 1-7, 12.2022
- Urheber
-
Fontes, Magda S. C.
Dingemanse, Jasper
Halabi, Atef
Tomaszewska-Kiecana, Monika
Sidharta, Patricia N.
- Beteiligte Personen und Organisationen
-
SpringerLink (Online service)
- DOI
-
10.1038/s41598-022-22470-z
- URN
-
urn:nbn:de:101:1-2023012322051267659962
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:19 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Fontes, Magda S. C.
- Dingemanse, Jasper
- Halabi, Atef
- Tomaszewska-Kiecana, Monika
- Sidharta, Patricia N.
- SpringerLink (Online service)
Ähnliche Objekte (12)
Safety, Tolerability and Pharmacokinetics of Single-Dose Oral SYHA1402 in Healthy Chinese Subjects
Structural basis of antagonist selectivity in endothelin receptors
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
A Phase I, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of AMG 986 in Healthy Japanese Subjects
Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes
Effekt von Endothelin-1 und Endothelin-A-Rezeptor-Antagonist auf die Mikrozirkulation bei TNBS-Colitis
Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep
The Pharmacokinetics of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone
First-in-Human Safety, Tolerability, and Pharmacokinetics of Single-Dose Kukoamine B Mesylate in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase I Study
The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and dose-escalation phase I trial
Safety, Tolerability and Pharmacokinetics of Single-Dose Oral SYHA1402 in Healthy Chinese Subjects
Structural basis of antagonist selectivity in endothelin receptors
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
A Phase I, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of AMG 986 in Healthy Japanese Subjects
Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes
Effekt von Endothelin-1 und Endothelin-A-Rezeptor-Antagonist auf die Mikrozirkulation bei TNBS-Colitis
Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep
The Pharmacokinetics of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone
First-in-Human Safety, Tolerability, and Pharmacokinetics of Single-Dose Kukoamine B Mesylate in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase I Study
The pharmacokinetics, pharmacodynamics and tolerability of SHR6508 in chinese healthy subjects: a randomized, placebo-controlled, double-blind, single-dose and dose-escalation phase I trial
Safety, Tolerability and Pharmacokinetics of Single-Dose Oral SYHA1402 in Healthy Chinese Subjects
Structural basis of antagonist selectivity in endothelin receptors
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
A Phase I, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of AMG 986 in Healthy Japanese Subjects
Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes
Effekt von Endothelin-1 und Endothelin-A-Rezeptor-Antagonist auf die Mikrozirkulation bei TNBS-Colitis
Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep
The Pharmacokinetics of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone
First-in-Human Safety, Tolerability, and Pharmacokinetics of Single-Dose Kukoamine B Mesylate in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase I Study